PLK2 - polo like kinase 2 Gene

Sus scrofa

Gene ID: 397251 | Gene type: protein coding

About PLK2

Primary_assembly 16: 37,299,119-37,305,114 reverse strand.Sscrofa11.1:CM000827.5

This gene has 2 transcripts (splice variants), 221 orthologues and 4 paralogues. Ubiquitous expression in lung (RPKM 39.7), kidney (RPKM 19.) and 8 other tissues.

PLK2 Products(1)

mRNA	Protein	Name
XM_003133981.5	XP_003134029.1	serine/threonine-protein kinase PLK2

PLK2 Protein Structure

STKc_PLK2

POLO_box_1

POLO_box_2

0
200
400
600
685 a.a.

Protein Preferred Names

Protein Names

serine/threonine-protein kinase PLK2

serum-inducible kinase

Related Agents

Approval

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12137	Volasertib	Inhibitor	99.97%	Yes
HY-12137A	Volasertib trihydrochloride	Inhibitor	99.12%	Yes

Clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Phase
HY-12037A	Rigosertib	Inhibitor	99.01%	Phase 3
HY-12037	Rigosertib sodium	Inhibitor	99.57%	Phase 3
HY-50698	BI 2536	Inhibitor	99.95%	Phase 2
HY-147298	Plogosertib	Inhibitor	98.59%	Phase 2
HY-15160	TAK-960	Inhibitor	99.75%	Phase 1
HY-15160B	TAK-960 dihydrochloride	Inhibitor	99.19%	Phase 1
HY-15160A	TAK-960 hydrochloride	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-100789	ON1231320	Inhibitor	99.90%	Unkown
HY-12134	Poloxin	Inhibitor	98.05%	Unkown
HY-108597	TC-S 7005	Inhibitor	99.68%	Unkown
HY-180896	8012–3246	Inhibitor	99.72%	Unkown
HY-173212	PLK1-IN-13	Inhibitor	/	Unkown
HY-172364	PLK1-IN-12	Inhibitor	/	Unkown
HY-115589	YLT-11	Inhibitor	/	Unkown
HY-149100	PLK1-IN-6	Inhibitor	/	Unkown
HY-181030	BDE30671203	Inhibitor	/	Unkown
HY-181051	PLK1-IN-16	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	PLK2	NCBI	NCBI:10769

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