Mfsd2b - MFSD2 lysolipid transporter B, sphingolipid Gene

Mus musculus

Also known as Gm1964

Gene ID: 432628 | Gene type: protein coding

About Mfsd2b

Summary

Enables sphingolipid transporter activity. Involved in lipid transport. Is integral component of plasma membrane. Is expressed in liver lobe. Orthologous to human MFSD2B (major facilitator superfamily domain containing 2B). [provided by Alliance of Genome Resources, Apr 2022]

Mfsd2b Products(1)

mRNA	Protein	Name
NM_001033488.2	NP_001028660.2	sphingosine-1-phosphate transporter MFSD2B

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables sphingolipid transporter activity	IDA IDA: Inferred from direct assay	29563527	MGI
enables sphingolipid transporter activity	IMP IMP: Inferred from mutant phenotype	29045386	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in lipid transport	IDA IDA: Inferred from direct assay	29563527	MGI
involved in lipid transport	IMP IMP: Inferred from mutant phenotype	29045386	MGI
involved in positive regulation of platelet aggregation	IMP IMP: Inferred from mutant phenotype	33863882	MGI
involved in sphingosine-1-phosphate receptor signaling pathway	IDA IDA: Inferred from direct assay	33785361	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in plasma membrane	IDA IDA: Inferred from direct assay	29563527	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	29045386	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

sphingosine-1-phosphate transporter MFSD2B

major facilitator superfamily domain-containing protein 2B

mMfsd2b	major facilitator superfamily domain containing 2B
major facilitator superfamily domain-containing protein 2b

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-182375A	SLB1122168 free base	Inhibitor	/	Unkown
HY-RS08392	MFSD2B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mfsd2b	NCBI	NCBI:388931

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