Mfsd2b - MFSD2 lysolipid transporter B, sphingolipid Gene

Also Known as Gm1964

Species: Mus musculus

Gene Type: protein coding
Gene ID: 432628

Summary

Enables sphingolipid transporter activity. Involved in lipid transport. Is integral component of plasma membrane. Is expressed in liver lobe. Orthologous to human MFSD2B (major facilitator superfamily domain containing 2B). [provided by Alliance of Genome Resources, Apr 2022]

Mfsd2b Products (1)

mRNA Protein Name
NM_001033488.2 NP_001028660.2 sphingosine-1-phosphate transporter MFSD2B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables sphingolipid transporter activity IDA
IDA: Inferred from direct assay
29563527 MGI
enables sphingolipid transporter activity IMP
IMP: Inferred from mutant phenotype
29045386 MGI
Biological Process GO Annotation Evidence References Source
involved in lipid transport IDA
IDA: Inferred from direct assay
29563527 MGI
involved in lipid transport IMP
IMP: Inferred from mutant phenotype
29045386 MGI
involved in positive regulation of platelet aggregation IMP
IMP: Inferred from mutant phenotype
33863882 MGI
involved in sphingosine-1-phosphate receptor signaling pathway IDA
IDA: Inferred from direct assay
33785361 MGI
Cellular Component GO Annotation Evidence References Source
is active in plasma membrane IDA
IDA: Inferred from direct assay
29563527 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
29045386 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sphingosine-1-phosphate transporter MFSD2B

major facilitator superfamily domain-containing protein 2B

  • mMfsd2b

  • major facilitator superfamily domain containing 2B

  • major facilitator superfamily domain-containing protein 2b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-182375A SLB1122168 free base Inhibitor / Unkown
HY-RS08392 MFSD2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mfsd2b NCBI NCBI:388931