MGMT - O-6-methylguanine-DNA methyltransferase Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 442978

About MGMT

Primary_assembly 28: 38,778,349-39,060,187 forward strand.ROS_Cfam_1.0:CM025127.1

This gene has 1 transcript (splice variant) and 189 orthologues.

MGMT Products (1)

mRNA Protein Name
NM_001003376.1 NP_001003376.1 methylated-DNA--protein-cysteine methyltransferase

MGMT Protein Structure

AdaB

AdaB: COG0350 (5 - 177)

  • 0
  • 100
  • 200
  • 216 a.a.
Protein Preferred Names Protein Names

methylated-DNA--protein-cysteine methyltransferase

  • 6-O-methylguanine-DNA methyltransferase

  • O-6-methylguanine-DNA-alkyltransferase

  • O6-alkylguanine-DNA-alkyltransferase

  • O6-methylguanine-DNA-methyltransferase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-13668 Lomeguatrib Inhibitor 99.77% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13057 O6BTG-octylglucoside Inhibitor 95.0% Unkown
HY-175299 Hedgehog IN-11 Inhibitor / Unkown
HY-186228 Anticancer agent 333 / Unkown
HY-180540 MGMT-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MGMT NCBI NCBI:4255