2. Gene
  3. Sacs - sacsin Gene

Sacs - sacsin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as DNAJC29; A230052M14; E130115J16Rik

Gene ID: 50720 | Gene type: protein coding

About Sacs

Summary

Predicted to enable several functions, including HSP70 protein binding activity; chaperone binding activity; and low-density lipoprotein particle receptor binding activity. Predicted to be involved in negative regulation of inclusion body assembly. Predicted to be located in mitochondrion and nucleus. Is expressed in dorsal root ganglion; facial ganglion; glossopharyngeal ganglion; trigeminal ganglion; and vagus ganglion. Used to study Charlevoix-Saguenay spastic ataxia. Human ortholog(s) of this gene implicated in Charlevoix-Saguenay spastic ataxia. Orthologous to human SACS (sacsin molecular chaperone). [provided by Alliance of Genome Resources, Apr 2022]

Sacs Products(2)

mRNA Protein Name
NM_015788.2 NP_056603.2 sacsin isoform 1
NM_172809.3 NP_766397.2 sacsin isoform 2
Protein Preferred Names Protein Names

sacsin

dnaJ homolog subfamily C member 29

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-128742 Thiamine monophosphate chloride dihydrate 99.24% Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-14644 Apilimod Inhibitor 99.80% Phase 2
HY-14644A Apilimod mesylate Inhibitor 99.58% Phase 2
Pre-clinical Phase
Bioactive Molecules (22)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1410 GsMTx4 Inhibitor 99.89% Unkown
HY-P1410A GsMTx4 TFA Inhibitor 99.85% Unkown
HY-151798 TDI-11861 Inhibitor 99.35% Unkown
HY-132298 TDI-10229 Inhibitor 99.00% Unkown
HY-103194 KH7 Inhibitor 99.0% Unkown
HY-135960 BO-264 99.76% Unkown
HY-100341 M2I-1 Inhibitor 98.0% Unkown
HY-W001538 S-Propargylcysteine 97.0% Unkown
HY-130841 Apcin-A Inhibitor 98.0% Unkown
HY-118282 mPGES1-IN-7 Inhibitor 99.78% Unkown
HY-170868 CL2A-FL118 / Unkown
HY-177531 S-Ac7-DOg 99.69% Unkown
HY-110347 Mps1-IN-1 dihydrochloride Inhibitor / Unkown
HY-116709 Junenol / Unkown
HY-161287 HDAC6-IN-32 Inhibitor / Unkown
HY-164955 TTK/PLK1-IN-1 Inhibitor / Unkown
HY-E71103 (R)-Mandelonitrile oxidase / Unkown
HY-N10597 5'''-O-Feruloyl complanatoside B / Unkown
HY-N16371 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid / Unkown
HY-RS12411 SACS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W127730 Pyridoxine 3,4-dipalmitate 99.99% Unkown
HY-W415799 (2S)-Ac4GalNAl / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sacs NCBI NCBI:26278