2. Gene
  3. Deaf1 - DEAF1, transcription factor Gene

Deaf1 - DEAF1, transcription factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as NUDR; C230009B13Rik

Gene ID: 54006 | Gene type: protein coding

About Deaf1

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including behavioral fear response; chordate embryonic development; and visual learning. Acts upstream of or within regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including bone; early conceptus; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Vulto-van Silfout-de Vries syndrome. Orthologous to human DEAF1 (DEAF1 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Deaf1 Products(4)

mRNA Protein Name
NM_001282072.1 NP_001269001.1 deformed epidermal autoregulatory factor 1 homolog isoform 2 precursor
NM_001282073.1 NP_001269002.1 deformed epidermal autoregulatory factor 1 homolog isoform 3
NM_001282076.1 NP_001269005.1 deformed epidermal autoregulatory factor 1 homolog isoform 4 precursor
NM_016874.3 NP_058570.1 deformed epidermal autoregulatory factor 1 homolog isoform 1
Protein Preferred Names Protein Names

deformed epidermal autoregulatory factor 1 homolog

nuclear DEAF-1-related transcriptional regulator

suppressin

Deaf1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Deaf1 Q9Z1T5 Mecp2 Mus musculus Q9Z2D6
Anti Bait CoIP
29636529
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-W004705 (2-Aminophenyl)methanol 99.82% Phase 2
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-E70231 Thrombin-like enzyme / Unkown
HY-RS03666 DEAF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Deaf1 NCBI NCBI:10522