MAPT - microtubule associated protein tau Gene

Also Known as TAU; PHF-tau

Species: Macaca mulatta

Gene Type: protein coding
Gene ID: 574327

About MAPT

Primary_assembly 16: 57,684,782-57,814,543 forward strand.Mmul_10:CM014351.1

This gene has 6 transcripts (splice variants), 225 orthologues and 1 paralogue.

MAPT Products (7)

mRNA Protein Name
XM_015119959.2 XP_014975445.1 microtubule-associated protein tau isoform X6
XM_015119958.2 XP_014975444.1 microtubule-associated protein tau isoform X5
XM_015119955.2 XP_014975441.1 microtubule-associated protein tau isoform X2
XM_015119954.2 XP_014975440.1 microtubule-associated protein tau isoform X1
XM_015119960.2 XP_014975446.1 microtubule-associated protein tau isoform X7
XM_015119957.2 XP_014975443.1 microtubule-associated protein tau isoform X4
XM_015119956.2 XP_014975442.1 microtubule-associated protein tau isoform X3

MAPT Protein Structure

PRK13108

PRK13108: cl36218 (34 - 171)

PHA03247

PHA03247: cl33720 (141 - 585)

Tubulin-binding

Tubulin-binding: pfam00418 (586 - 607)

Tubulin-binding

Tubulin-binding: pfam00418 (609 - 638)

Tubulin-binding

Tubulin-binding: pfam00418 (640 - 669)

Tubulin-binding

Tubulin-binding: pfam00418 (671 - 701)

  • 0
  • 200
  • 400
  • 600
  • 776 a.a.
Protein Preferred Names Protein Names

microtubule-associated protein tau

  • Neurofibrillary tangle protein

  • Paired helical filament-tau

Recombinant MAPT Proteins

Cat. No. Product Name Accession Purity
HY-P700423 Tau-A/MAPT Protein, Macaca mulatta (HEK293, His) P57786-1 (A2-L459) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-132582 Diranersen Inhibitor 93.23% Phase 2
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991373 APNmAb005 Inhibitor 97.64% Phase 1

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-132582C Diranersen sodium Inhibitor 91.82% Unkown
HY-P4808A PHF6 TFA Activator 99.45% Unkown
HY-P4808 PHF6 Activator 99.17% Unkown
HY-147149 BPN-15477 Modulator 99.92% Unkown
HY-RS08140 MAPT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08141 Mapt Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174215 TAU-IN-3 Inhibitor / Unkown
HY-RS08142 Mapt Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MAPT NCBI NCBI:4137