Tnfrsf13b - tumor necrosis factor receptor superfamily, member 13b Gene

Also Known as Taci; 1200009E08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57916

Summary

Acts upstream of or within B cell homeostasis; hematopoietic progenitor cell differentiation; and negative regulation of B cell proliferation. Located in external side of plasma membrane. Is integral component of plasma membrane. Is expressed in renal vasculature. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human TNFRSF13B (TNF Receptor Superfamily member 13B). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf13b Products (1)

mRNA Protein Name
NM_021349.3 NP_067324.1 tumor necrosis factor receptor superfamily member 13B

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within B cell homeostasis IDA
IDA: Inferred from direct assay
14707116 MGI
acts upstream of or within B cell homeostasis IMP
IMP: Inferred from mutant phenotype
15240667 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: Inferred from mutant phenotype
24029230 MGI
acts upstream of or within negative regulation of B cell proliferation IMP
IMP: Inferred from mutant phenotype
15240667 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
15240667 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10920230 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor receptor superfamily member 13B

  • transmembrane activator and CAML interactor

  • transmembrane activator and calcium-modulating and cyclophilin ligand interactor

Recombinant Tnfrsf13b Proteins

Cat. No. Product Name Accession Purity
HY-P72457 TNFRSF13B Protein, Mouse (HEK293, Fc) Q9ET35 (F5-T129) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14804 TNFRSF13B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18321 Tnfrsf13b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24799 Tnfrsf13b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfrsf13b NCBI NCBI:23495