2. Gene
  3. Crhr1 - corticotropin releasing hormone receptor 1 Gene

Crhr1 - corticotropin releasing hormone receptor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CRF1; CRF-R; CRFR1; CRH-R; CRF-R1; CRFR-1; CRH-R1; CRF-R-1; CRH-R 1; CRH-R-1

Gene ID: 58959 | Gene type: protein coding

About Crhr1

Primary_assembly 10: 89,040,203-89,083,481 forward strand.mRatBN7.2:CM026983.1

This gene has 2 transcripts (splice variants), 239 orthologues, 42 paralogues and is associated with 29 phenotypes. Restricted expression toward (RPKM 31.6).

Summary

This gene encodes a member of the G-protein coupled receptor family. The encoded protein is a receptor for corticotropin-releasing factor (CRH) and urocortin (UCN). The interaction of this protein with CRH and UCN triggers G-protein coupled signaling. This protein plays a pivotal role in mediating the CRH-elicited effects in depression and anxiety. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

Crhr1 Products(2)

mRNA Protein Name
NM_001301812.2 NP_001288741.2 corticotropin-releasing factor receptor 1 isoform 2 precursor
NM_030999.5 NP_112261.2 corticotropin-releasing factor receptor 1 isoform 1 precursor
Protein Preferred Names Protein Names

corticotropin-releasing factor receptor 1

corticotrophin releasing hormone receptor 1

corticotropin releasing hormone 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103377 Antalarmin hydrochloride Antagonist 99.87% Unkown
HY-12131 DMP 696 Antagonist 99.03% Unkown
HY-124475 Antalarmin Antagonist / Unkown
HY-RS03168 CRHR1 Human Pre-designed siRNA Set A / Unkown
HY-RS03169 Crhr1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS03170 Crhr1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crhr1 NCBI NCBI:1394