Pttg1 - PTTG1 regulator of sister chromatid separation, securin Gene

Also Known as Pttg

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64193

Summary

Enables heat shock protein binding activity and ribosome binding activity. Involved in negative regulation of cell population proliferation and regulation of cell growth. Predicted to be located in cytosol. Predicted to be active in nucleus. Orthologous to several human genes including PTTG1 (PTTG1 regulator of sister chromatid separation, securin). [provided by Alliance of Genome Resources, Apr 2022]

Pttg1 Products (1)

mRNA Protein Name
NM_022391.3 NP_071786.1 securin

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables heat shock protein binding IPI
IPI: Inferred from physical interaction
9915854 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9915854 RGD
enables ribosome binding IPI
IPI: Inferred from physical interaction
9915854 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
9092795 RGD
involved in regulation of cell growth IMP
IMP: Inferred from mutant phenotype
9092795 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

securin

  • Pituitary tumor transforming

  • pituitary tumor-transforming 1

  • pituitary tumor-transforming gene 1 protein

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-10424A Milciclib maleate Inhibitor / Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N8146 Bruceantinol Inhibitor 98.89% Unkown
HY-RS11456 PTTG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19029 Pttg1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25518 Pttg1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pttg1 NCBI NCBI:9232