Insig1 - insulin induced gene 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64194

Summary

Predicted to enable oxysterol binding activity. Involved in cellular response to Insulin stimulus; response to estradiol; and response to fatty acid. Predicted to be part of SREBP-SCAP-Insig complex. Predicted to be active in endoplasmic reticulum. Biomarker of fatty liver disease. Orthologous to human INSIG1 (Insulin induced gene 1). [provided by Alliance of Genome Resources, Apr 2022]

Insig1 Products (1)

mRNA Protein Name
NM_022392.2 NP_071787.1 insulin-induced gene 1 protein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
19299314 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
12801995 RGD
involved in response to fatty acid IEP
IEP: Inferred from expression pattern
16222032 RGD
involved in response to lipid IEP
IEP: Inferred from expression pattern
17709436 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
18801905 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

insulin-induced gene 1 protein

  • INSIG-1

  • growth response protein (CL-6)

  • immediate-early protein CL-6

  • insulin-induced growth response protein CL-6

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-109056 Elsulfavirine Inhibitor 99.90% Unkown

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-109056A Elsulfavirine sodium Inhibitor / Unkown
HY-121012 (rac)-AG-205 / Unkown
HY-N20666 Canola oil / Unkown
HY-RS06837 INSIG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17851 Insig1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24319 Insig1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Insig1 NCBI NCBI:3638