Uvrag - UV radiation resistance associated gene Gene

Also Known as Uvrag1; Uvragl; 9530039D02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78610

Summary

Enables SH3 domain binding activity and SNARE binding activity. Involved in DNA repair; chromosome segregation; and microtubule Cytoskeleton organization. Acts upstream of or within SNARE complex assembly and viral entry into host cell. Located in phagocytic vesicle. Part of protein-containing complex. Is expressed in midgut; smooth muscle tissue; and thyroid gland. Orthologous to human UVRAG (UV radiation resistance associated). [provided by Alliance of Genome Resources, Apr 2022]

Uvrag Products (1)

mRNA Protein Name
NM_178635.3 NP_848750.3 UV radiation resistance-associated protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SH3 domain binding IPI
IPI: Inferred from physical interaction
17891140 MGI
enables SNARE binding IDA
IDA: Inferred from direct assay
24550300 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17891140 MGI
Biological Process GO Annotation Evidence References Source
involved in DNA repair IMP
IMP: Inferred from mutant phenotype
22542840 MGI
acts upstream of or within SNARE complex assembly IMP
IMP: Inferred from mutant phenotype
24550300 MGI
involved in centrosome cycle IMP
IMP: Inferred from mutant phenotype
22542840 MGI
involved in chromosome segregation IMP
IMP: Inferred from mutant phenotype
22542840 MGI
involved in spindle organization IMP
IMP: Inferred from mutant phenotype
22542840 MGI
acts upstream of or within symbiont entry into host cell IMP
IMP: Inferred from mutant phenotype
24550300 MGI
Cellular Component GO Annotation Evidence References Source
located in phagocytic vesicle IPI
IPI: Inferred from physical interaction
22493499 MGI
part of protein-containing complex IDA
IDA: Inferred from direct assay
17891140 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

UV radiation resistance-associated protein

  • UV radiation resistance associated protein

  • UV radiation resistance-associated gene protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-156237 Beclin1-ATG14L interaction inhibitor 1 Inhibitor 99.88% Unkown
HY-152100 CUR5g Inhibitor 98.69% Unkown
HY-183987 ZINC000002107582 / Unkown
HY-RS15588 UVRAG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uvrag NCBI NCBI:7405