2. Gene
  3. Rab1a - RAB1A, member RAS oncogene family Gene

Rab1a - RAB1A, member RAS oncogene family Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Rab1; Rab1r; Ac2-048

Gene ID: 81754 | Gene type: protein coding

About Rab1a

Summary

Enables GTP binding activity. Involved in endocytosis and vesicle transport along microtubule. Acts upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport. Located in several cellular components, including Golgi membrane; early endosome; and neuronal cell body. Is active in presynapse. Orthologous to human RAB1A (RAB1A, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab1a Products(1)

mRNA Protein Name
NM_031090.3 NP_112352.2 ras-related protein Rab-1A
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GTP binding IDA
IDA: Inferred from direct assay
8807639 RGD
Biological Process GO Annotation Evidence Reference Source
involved in endocytosis IMP
IMP: Inferred from mutant phenotype
21303926 RGD
acts upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport IDA
IDA: Inferred from direct assay
15728249 RGD
involved in vesicle transport along microtubule IMP
IMP: Inferred from mutant phenotype
21303926 RGD
Cellular Component GO Annotation Evidence Reference Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
8807639 RGD
located in early endosome IDA
IDA: Inferred from direct assay
21303926 RGD
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
8807639 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
8573789 RGD
is active in presynapse EXP
EXP: Inferred from Experiment
23622064 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
23622064 RGD
located in presynapse IDA
IDA: Inferred from direct assay
20926670 RGD
is active in synapse EXP
EXP: Inferred from Experiment
24876496 RGD
is active in synapse IDA
IDA: Inferred from direct assay
24876496 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-1A

RAB1, member RAS oncogene family

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-110174 NAB2 Degrader 99.69% Unkown
HY-156242 BQZ-485 Inducer / Unkown
HY-RS11528 RAB1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22758 Rab1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab1a NCBI NCBI:5861