MMV019662
MMV019662 is a PfNCR1 inhibitor and antimalarial agent. MMV019662 reduces gametocytemia levels of Plasmodium falciparum. MMV019662 is applicable to malaria-related research.
For research use only. We do not sell to patients.
- CAS No.: 896349-19-2
- Formula: C27H35N3O4
- Molecular Weight:465.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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Plasmodium |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | Inhibition |
1 %
Compound: TCMDC-124312
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GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM.
GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM.
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[PMID: 20485427] |
MMV019662 (3× EC90; 13 days) significantly reduces the total gametocytaemia level of blood-stage gametocytes of Plasmodium falciparum[1].
MMV019662 (72 h) inhibits the growth of the asexual erythrocytic stage of P. falciparum (Plasmodium falciparum) with an EC50 of 1.18 μM[1].
MMV019662 (0-100 μM) does not thermostabilize purified PfNCR1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 896349-19-2
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Molecular Weight 465.59
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Formula C27H35N3O4
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SMILES
O=C(NCC(C1=CC=C2OCOC2=C1)N3CCN(C4=CC=C(OC)C=C4)CC3)C5CCCCC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MMV019662 Related Classifications
HY-164686 Related Classifications
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