4'-Methoxyflavone
Based on 1 Customer Validation
4'-Methoxyflavone is a flavonoid with antioxidant properties and anti-proliferative activity against cancer cells. 4'-Methoxyflavone can inhibit cycle-dependent kinases leading to cell cycle arrest and regulate cell signaling pathways to influence cell proliferation and apoptosis. 4'-Methoxyflavone can be used in cancer chemoprevention research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.63%
- CAS 番号: 4143-74-2
- 分子式: C16H12O3
- 分子量:252.26
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BTI-TN-5B1-4 | IC50 |
27.87 μM
Compound: 3d
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Inhibition of human recombinant MAOB expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assay
Inhibition of human recombinant MAOB expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assay
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[PMID: 20045650] |
| MCF7 | GI50 |
61.8 μM
Compound: 1e
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Cytotoxicity against Homo sapiens (human) MCF7 cells after 48 hr by SRB assay
Cytotoxicity against Homo sapiens (human) MCF7 cells after 48 hr by SRB assay
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10.1007/s00044-012-0423-1 |
| MDCK | CC50 |
191.8 μM
Compound: 1f
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Cytotoxicity against dog MDCK cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability by MTT assay
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[PMID: 31744778] |
| MDCK | EC50 |
9.36 nM
Compound: 1f
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Antiviral activity against Influenza A virus (H1N1) infected in dog MDCK cells assessed as reduction in log2HA titer incubated for 3 to 4 days by CPE assay
Antiviral activity against Influenza A virus (H1N1) infected in dog MDCK cells assessed as reduction in log2HA titer incubated for 3 to 4 days by CPE assay
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[PMID: 31744778] |
| MOLT-4 | GI50 |
99.2 μM
Compound: 1e
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Cytotoxicity against Homo sapiens (human) MOLT4 cells after 48 hr by SRB assay
Cytotoxicity against Homo sapiens (human) MOLT4 cells after 48 hr by SRB assay
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10.1007/s00044-012-0423-1 |
化学情報
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CAS 番号 4143-74-2
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性状 Solid
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分子量 252.26
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分子式 C16H12O3
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Color White to off-white
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SMILES
O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC=CC=C13
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 10 mg/mL (39.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9642 mL | 19.8208 mL | 39.6416 mL | 99.1041 mL |
| 5 mM | 0.7928 mL | 3.9642 mL | 7.9283 mL | 19.8208 mL | |
| 10 mM | 0.3964 mL | 1.9821 mL | 3.9642 mL | 9.9104 mL | |
| 15 mM | 0.2643 mL | 1.3214 mL | 2.6428 mL | 6.6069 mL | |
| 20 mM | 0.1982 mL | 0.9910 mL | 1.9821 mL | 4.9552 mL | |
| 25 mM | 0.1586 mL | 0.7928 mL | 1.5857 mL | 3.9642 mL | |
| 30 mM | 0.1321 mL | 0.6607 mL | 1.3214 mL | 3.3035 mL |
4'-Methoxyflavone 関連分類
HY-139054 関連分類
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