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製品番号: HY-N2108

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7-Ethylcamptothecin

(別名: 7-エチルカンプトテシン)

カスタマーレビュー

Based on 1 Customer Validation

7-Ethylcamptothecin is a derivative of Camptothecin (HY-16560) and a DNA topoisomerase I inhibitor that exhibits significant antitumor activity against tumor cells. 7-Ethylcamptothecin serves as a key precursor for the synthesis of 20 (S)-O-substituted benzoyl-7-ethylcamptothecin compounds. 7-Ethylcamptothecin is widely used in various tumor-related scientific studies.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度: 99.58%
CAS 番号: 78287-27-1
分子式: C₂₂H₂₀N₂O₄
分子量:376.41

保管条件:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

7-Ethylcamptothecin 構造式

CAS 番号: 78287-27-1

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Topoisomerase アイソフォーム固有の製品をすべて表示 :

体外実験

7-Ethylcamptothecin serves as a starting material for the development of E-ring modified water-soluble camptothecin derivatives, and exhibits favorable antitumor activity^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 78287-27-1
性状 Solid
分子量 376.41
分子式 C₂₂H₂₀N₂O₄
Color Light yellow to yellow
SMILES

O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CC)C5=CC=CC=C5N=C4C3=C2)=O
別名

7-エチルカンプトテシン
Structure Classification
- Alkaloids
- Quinoline Alkaloids
Initial Source
- Plants
- other families
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 5 mg/mL (13.28 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.6567 mL

13.2834 mL

26.5668 mL

5 mM

0.5313 mL

2.6567 mL

5.3134 mL

10 mM

0.2657 mL

1.3283 mL

2.6567 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (277 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Liu Y, et al. A novel camptothecin derivative 3j inhibits Nsclc proliferation via induction of cell cycle arrest by topo I-mediated DNA damage[J]. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents), 2019, 19(3): 365-374.

[2]. Kaneda N, et al. Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse[J]. Cancer research, 1990, 50(6): 1715-1720.

[3]. Supko J G, et al. Pharmacokinetics of the 9-amino and 10, 11-methylenedioxy derivatives of camptothecin in mice[J]. Cancer research, 1993, 53(13): 3062-3069.

[4]. Sawada S, et al. Chemical modification of an antitumor alkaloid, 20 (S)-camptothecin: E-lactone ring-modified water-soluble derivatives of 7-ethylcamptothecin[J]. Chemical and pharmaceutical bulletin, 1993, 41(2): 310-313.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.6567 mL	13.2834 mL	26.5668 mL	66.4169 mL
	5 mM	0.5313 mL	2.6567 mL	5.3134 mL	13.2834 mL
	10 mM	0.2657 mL	1.3283 mL	2.6567 mL	6.6417 mL

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

生物活性
- 製品説明
- 体外実験
化学情報
溶剤 & 溶解度
- 体外実験
純度とドキュメンテーション
参考文献

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製品番号:
数量:
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7-Ethylcamptothecin

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Natural Product Library

Anti-Cancer Compound Library

Anti-Aging Compound Library

Topoisomerase アイソフォーム固有の製品をすべて表示

生物活性

化学情報

溶剤 & 溶解度

純度とドキュメンテーション

参考文献

Help & FAQs

Complete Stock Solution Preparation Table

7-Ethylcamptothecin

Traditional Chinese Medicine Active Compound Library

Alkaloids Library

Anti-Lung Cancer Compound Library

Anti-Cancer Natural Product Library

Plant-Sourced Natural Product Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Natural Product Library Plus

Bioactive Compound Library

Protein Kinase Compound Library

RO5 Drug-like Natural Product Library

High-Throughput Bioactive Compound Library

High-Throughput Natural Product Library

Mass Spectrometry Natural Product Library

Natural Product and Natural Product-Like Compound Library

Cell Cycle/DNA Damage Compound Library

Natural Product Library

Anti-Cancer Compound Library

Anti-Aging Compound Library

Topoisomerase アイソフォーム固有の製品をすべて表示

生物活性

化学情報

溶剤 & 溶解度

純度とドキュメンテーション

参考文献

Help & FAQs

Complete Stock Solution Preparation Table

7-Ethylcamptothecin 関連分類

HY-N2108 関連分類