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United States

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製品番号: HY-146051

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Antitubercular agent-18

Antitubercular agent-18 (Compound 9a) is an antitubercular agent with MIC values of 2, 2, 2 and 128 µg/ml against M. tuberculosis H37Rv, Spec. 192, Spec 210 and Spec. 800, respectively. Antitubercular agent-18 shows highly selective antimycobacterial effects.

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CAS 番号: 1308272-99-2
分子式: C₁₄H₁₂BrN₅O
分子量:346.18

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Antitubercular agent-18 構造式

CAS 番号: 1308272-99-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
HaCaT	IC₅₀	131.26 μM Compound: 9a	Cytotoxicity against human HaCaT cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human HaCaT cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 31753514]
V79	IC₅₀	212.46 μM Compound: 9a	Cytotoxicity against Chinese Hamster V79 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against Chinese Hamster V79 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 31753514]

化学情報

CAS 番号 1308272-99-2
分子量 346.18
分子式 C₁₄H₁₂BrN₅O
SMILES

COC1=CC=C(N2N=NN=C2NC3=CC=C(Br)C=C3)C=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (269 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Szulczyk D, et al. Development of (4-methoxyphenyl)-1H-tetrazol-5-amine regioisomers as a new class of selective antitubercular agents. Eur J Med Chem. 2020 Jan 15;186:111882. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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