CDK5-IN-1
Based on 1 publication(s) in Google Scholar
CDK5-IN-1 is a potent CDK5 inhibitor with an IC50 less than 10 nM. CDK5-IN-1 is greater than 100-fold more active against CDK5 than CDK2. CDK5-IN-1 is used for kidney diseases research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.47%
- CAS 番号: 2639540-19-3
- 分子式: C24H25FN6O3S
- 分子量:496.56
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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MedChemExpress（MCE）の使用を引用している文献 CDK5-IN-1
More
生物活性
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CDK5 < 10 nM (IC50) |
化学情報
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CAS 番号 2639540-19-3
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性状 Solid
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分子量 496.56
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分子式 C24H25FN6O3S
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Color Yellow to orange
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SMILES
O=S(C1=CC=C2C=NC(NC3=CC=C(N4N=C(CO)C=C4)C=C3F)=CC2=N1)(C5CCN(CC5)C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Med
Inactivation of TACC2 epigenetically represses CDKN1A and confers sensitivity to CDK inhibitors. [Abstract]2025 Jan 5:100568. PMID: 39793578
溶剤 & 溶解度
DMSO : 250 mg/mL (503.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0139 mL | 10.0693 mL | 20.1386 mL | 50.3464 mL |
| 5 mM | 0.4028 mL | 2.0139 mL | 4.0277 mL | 10.0693 mL | |
| 10 mM | 0.2014 mL | 1.0069 mL | 2.0139 mL | 5.0346 mL | |
| 15 mM | 0.1343 mL | 0.6713 mL | 1.3426 mL | 3.3564 mL | |
| 20 mM | 0.1007 mL | 0.5035 mL | 1.0069 mL | 2.5173 mL | |
| 25 mM | 0.0806 mL | 0.4028 mL | 0.8055 mL | 2.0139 mL | |
| 30 mM | 0.0671 mL | 0.3356 mL | 0.6713 mL | 1.6782 mL | |
| 40 mM | 0.0503 mL | 0.2517 mL | 0.5035 mL | 1.2587 mL | |
| 50 mM | 0.0403 mL | 0.2014 mL | 0.4028 mL | 1.0069 mL | |
| 60 mM | 0.0336 mL | 0.1678 mL | 0.3356 mL | 0.8391 mL | |
| 80 mM | 0.0252 mL | 0.1259 mL | 0.2517 mL | 0.6293 mL | |
| 100 mM | 0.0201 mL | 0.1007 mL | 0.2014 mL | 0.5035 mL |
CDK5-IN-1 関連分類
HY-139725 関連分類
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