Garsevil
Garsevil (LSL 60101) is a biphasic, selective imidazoline I2 receptor (I2-IR) ligand, with a pKi of 9.03 and a Ki of 0.9 nM at the high-affinity site, and a pKi of 5.25 and a Ki of 5.6 nM at the low-affinity site. Garsevil is applicable to research related to Alzheimer's disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 150985-54-9
- 分子式: C11H8N2O
- 分子量:184.20
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Garsevil exhibits excellent selectivity for I2-IR over α2-adrenergic receptors (α2-AR), with an I2/α2 selectivity ratio of 7244.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 150985-54-9
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分子量 184.20
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分子式 C11H8N2O
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SMILES
N=1C=CNC1C=2OC=3C=CC=CC3C2
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別名
LSL 60101
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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- Garsevil
- 150985-54-9
- LSL 60101
- LSL60101
- LSL-60101
- neuroinflammatory gene expression
- α2-adrenergic receptors
- alzheimer’s disease
- adult Sprague-Dawley rats
- human I2-IR
- imidazoline I2 receptor
- human prefrontal cortex I2-imidazoline receptors
- hippocampal FADD protein
- 5-month-old female 5xFAD mice
- adult CD-1 mice
- Inhibitor
- inhibitor
- inhibit