ANGPTL7 - angiopoietin like 7 Gene

Also Known as AngX; CDT6; dJ647M16.1

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 10218

About ANGPTL7

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:11,189,355-11,195,981 (from NCBI)

This gene has 2 transcripts (splice variants), 316 orthologues and 25 paralogues. Broad expression in heart (RPKM 2.5), gall bladder (RPKM 2.2) and 15 other tissues.

Summary

Enables identical protein binding activity. Involved in negative regulation of vasculature development involved in avascular cornea development in camera-type eye and regulation of extracellular matrix organization. Located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

ANGPTL7 Products (1)

mRNA Protein Name
NM_021146.4 NP_066969.1 angiopoietin-related protein 7 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables identical protein binding IDA
IDA: Inferred from direct assay
11682471 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25910212 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in negative regulation of vasculature development involved in avascular cornea development in camera-type eye IMP
IMP: Inferred from mutant phenotype
25622036 GOA
involved in regulation of extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
21199193 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in extracellular region IDA
IDA: Inferred from direct assay
11682471 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

angiopoietin-related protein 7

  • angiopoietin-like factor (CDT6)

Recombinant ANGPTL7 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P7509 ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, His) O43827 (Q27-P346) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P78932 ANGPTL7/Angiopoietin-related 7 Protein, Human (Biotinylated, HEK293, mFc-Avi) O43827 (Q27-P346) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P700852 ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, hFc) O43827 (Q27-P346) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P700955 ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, His-Avi) O43827 (Q27-P346) ≥ 95%, as determined by reducing SDS-PAGE.

ANGPTL7 抗体

製品番号 製品名 アプリケーション 反応性
HY-P811028 ANGPTL7/ CDT6 Antibody WB, IHC-P Human, Mouse, Rat

関連疾患

Diseases Alias
Steroid-Induced Glaucoma

  • Corticosteroid-Induced Glaucoma
Schnyder Corneal Dystrophy

  • Schnyder Crystalline Corneal Dystrophy

  • SCCD

  • Corneal Dystrophy, Crystalline, Of Schnyder

  • Corneal Dystrophy, Schnyder Type

  • Corneal Dystrophy Crystalline Of Schnyder

  • Crystalline Stromal Dystrophy

  • Hereditary Crystalline Stromal Dystrophy Of Schnyder

  • Scd

  • Corneal Dystrophy, Schnyder

  • Schnyder Crystalline Dystrophy Sine Crystals

  • Dystrophy, Corneal, Crystalline, Schnyder
Glaucoma, Primary Open Angle

  • Glaucoma 1, Open Angle, E

  • Primary Open Angle Glaucoma

  • POAG

  • Adult-Onset Primary Open Angle Glaucoma

  • Chronic Simple Glaucoma

  • GLC1E

  • Primary Open Angle Glaucoma 1e

  • Glaucoma, Open Angle, Primary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS00696 ANGPTL7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17280 Angptl7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23735 Angptl7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus ANGPTL7 VGNC VGNC:25895
Canis familiaris ANGPTL7 VGNC VGNC:37863
Macaca mulatta ANGPTL7 VGNC VGNC:69683
Rattus norvegicus ANGPTL7 RGD RGD:7553363
Felis catus ANGPTL7 VGNC VGNC:59783
Mus musculus ANGPTL7 MGD MGI:3605801
Others ANGPTL7 NCBI