Rbl1 - RB transcriptional corepressor like 1 Gene

Also Known as PRB1; p107

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 19650

Summary

Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and promoter-specific chromatin binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; limb; liver; and retina. Orthologous to human RBL1 (RB transcriptional corepressor like 1). [provided by Alliance of Genome Resources, Apr 2022]

Rbl1 Products (2)

mRNA Protein Name
NM_001139516.1 NP_001132988.1 retinoblastoma-like protein 1 isoform 2
NM_011249.2 NP_035379.2 retinoblastoma-like protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
7797074 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7797074 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
15701640 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in nucleus IDA
IDA: Inferred from direct assay
10082561 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
10082561 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinoblastoma-like protein 1

  • 107 kDa retinoblastoma-associated protein

  • retinoblastoma-like 1 (p107)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Phase
HY-105024 FPL 62064 Inhibitor 99.25% Phase 3

Pre-clinical Phase

Bioactive Molecules (2)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-N12231 Carbazomycin B Inhibitor / Unkown
HY-RS11729 RBL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Rbl1 NCBI NCBI:5933