SLC38A7 - solute carrier family 38 member 7 Gene
Also Known as SNAT7
生物種: Homo sapiens
遺伝子タイプ: protein coding
遺伝子ID: 55238
About SLC38A7
Cytogenetic location: 16q21
Genomic coordinates (GRCh38): 16:58,665,109-58,684,770 (from NCBI)
This gene has 16 transcripts (splice variants), 242 orthologues and 15 paralogues. Broad expression in testis (RPKM 12.2), brain (RPKM 4.6) and 23 other tissues.
Summary
Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport and sodium ion transport. Predicted to be located in axon and neuronal cell body. [provided by Alliance of Genome Resources, Apr 2022]
SLC38A7 Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001308384.2 | NP_001295313.1 | putative sodium-coupled neutral amino acid transporter 7 isoform 2 |
| NM_001369608.1 | NP_001356537.1 | putative sodium-coupled neutral amino acid transporter 7 isoform 1 |
| NM_001369609.1 | NP_001356538.1 | putative sodium-coupled neutral amino acid transporter 7 isoform 1 |
| NM_001369610.1 | NP_001356539.1 | putative sodium-coupled neutral amino acid transporter 7 isoform 2 |
| NM_001369611.1 | NP_001356540.1 | putative sodium-coupled neutral amino acid transporter 7 isoform 1 |
| NM_018231.3 | NP_060701.1 | putative sodium-coupled neutral amino acid transporter 7 isoform 1 |
| Molecular Function GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| enables L-asparagine:sodium symporter activity |
IDA
IDA: Inferred from direct assay
|
28416685 | GOA |
| enables L-glutamine:sodium symporter activity |
IDA
IDA: Inferred from direct assay
|
28416685 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25416956 | GOA |
| Biological Process GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| involved in asparagine transport |
IDA
IDA: Inferred from direct assay
|
28416685 | GOA |
| involved in glutamine transport |
IDA
IDA: Inferred from direct assay
|
28416685 | GOA |
| Cellular Component GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| located in lysosomal membrane |
IDA
IDA: Inferred from direct assay
|
35561222 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
SLC38A7 Protein Structure
Aa_trans
Aa_trans: Transmembrane amino acid transporter protein (50 - 446)
- 0
- 100
- 200
- 300
- 400
- 462 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
putative sodium-coupled neutral amino acid transporter 7 |
|
SLC38A7 Protein-protein interaction Information
|
Type
|
タンパク質名 | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | 参考文献 |
|---|---|---|---|---|---|---|---|
|
Intra
|
SLC38A7 | Q9NVC3 | IL10RA | Homo sapiens | Q13651 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | IL10RA | Homo sapiens | Q13651 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | LYVE1 | Homo sapiens | Q9Y5Y7 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | LYVE1 | Homo sapiens | Q9Y5Y7 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | LYVE1 | Homo sapiens | Q9Y5Y7 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | CYB5R3 | Homo sapiens | P00387 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | CYB5R3 | Homo sapiens | P00387 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ACBD5 | Homo sapiens | Q5T8D3-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ACBD5 | Homo sapiens | Q5T8D3-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | TMEM237 | Homo sapiens | Q96Q45-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | TMEM237 | Homo sapiens | Q96Q45-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SLC6A15 | Homo sapiens | Q9H2J7 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SLC6A15 | Homo sapiens | Q9H2J7 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SPINT1 | Homo sapiens | O43278-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SPINT1 | Homo sapiens | O43278-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ODF4 | Homo sapiens | Q2M2E3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ODF4 | Homo sapiens | Q2M2E3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | AQP2 | Homo sapiens | P41181 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | AQP2 | Homo sapiens | P41181 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | OPRM1 | Homo sapiens | P35372-10 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | OPRM1 | Homo sapiens | P35372-10 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | GPR152 | Homo sapiens | Q8TDT2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | GPR152 | Homo sapiens | Q8TDT2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | PDCD1LG2 | Homo sapiens | Q9BQ51 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | PDCD1LG2 | Homo sapiens | Q9BQ51 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SCN3B | Homo sapiens | Q9NY72 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SCN3B | Homo sapiens | Q9NY72 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SCN3B | Homo sapiens | Q9NY72 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | MUC1 | Homo sapiens | P15941-11 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | MUC1 | Homo sapiens | P15941-11 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SSMEM1 | Homo sapiens | Q8WWF3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SSMEM1 | Homo sapiens | Q8WWF3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | AQP9 | Homo sapiens | O43315 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | AQP9 | Homo sapiens | O43315 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | GJA8 | Homo sapiens | P48165 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | GJA8 | Homo sapiens | P48165 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SLC18A1 | Homo sapiens | P54219-3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SLC18A1 | Homo sapiens | P54219-3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | EVI2B | Homo sapiens | P34910-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | EVI2B | Homo sapiens | P34910-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | BTNL9 | Homo sapiens | Q6UXG8-3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | BTNL9 | Homo sapiens | Q6UXG8-3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | CPLX4 | Homo sapiens | Q7Z7G2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | CPLX4 | Homo sapiens | Q7Z7G2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SHISAL1 | Homo sapiens | Q3SXP7 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SHISAL1 | Homo sapiens | Q3SXP7 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | GPR42 | Homo sapiens | O15529 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | GPR42 | Homo sapiens | O15529 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | TMEM52B | Homo sapiens | Q4KMG9 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | TMEM52B | Homo sapiens | Q4KMG9 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SYPL2 | Homo sapiens | Q5VXT5-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SYPL2 | Homo sapiens | Q5VXT5-2 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | AMIGO1 | Homo sapiens | Q86WK6 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | AMIGO1 | Homo sapiens | Q86WK6 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | APH1A | Homo sapiens | Q96BI3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | APH1A | Homo sapiens | Q96BI3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | HHLA2 | Homo sapiens | Q9UM44 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | HHLA2 | Homo sapiens | Q9UM44 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | HHLA2 | Homo sapiens | Q9UM44 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | CLEC10A | Homo sapiens | Q8IUN9 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | CLEC10A | Homo sapiens | Q8IUN9 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | RNF5 | Homo sapiens | Q99942 | 25416956 | |
|
Intra
|
SLC38A7 | Q9NVC3 | RNF5 | Homo sapiens | Q99942 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | RNF5 | Homo sapiens | Q99942 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | RNF5 | Homo sapiens | Q99942 | 25416956 | |
|
Intra
|
SLC38A7 | Q9NVC3 | GJB5 | Homo sapiens | O95377 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | GJB5 | Homo sapiens | O95377 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | FKBP7 | Homo sapiens | Q9Y680 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | FKBP7 | Homo sapiens | Q9Y680 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | FKBP7 | Homo sapiens | Q9Y680 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SAR1A | Homo sapiens | Q9NR31 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SAR1A | Homo sapiens | Q9NR31 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SLC10A1 | Homo sapiens | Q14973 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SLC10A1 | Homo sapiens | Q14973 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | TSPAN8 | Homo sapiens | P19075 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | TSPAN8 | Homo sapiens | P19075 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | EDA | Homo sapiens | Q92838 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | EDA | Homo sapiens | Q92838 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | MMGT1 | Homo sapiens | Q8N4V1 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | MMGT1 | Homo sapiens | Q8N4V1 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | PANX1 | Homo sapiens | Q96RD7 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | PANX1 | Homo sapiens | Q96RD7 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | CLDN7 | Homo sapiens | O95471 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | CLDN7 | Homo sapiens | O95471 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | YIPF6 | Homo sapiens | Q96EC8 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | YIPF6 | Homo sapiens | Q96EC8 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | CREB3L3 | Homo sapiens | Q68CJ9 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | CREB3L3 | Homo sapiens | Q68CJ9 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | KIR2DL3 | Homo sapiens | P43628 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | KIR2DL3 | Homo sapiens | P43628 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SLC30A2 | Homo sapiens | Q9BRI3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | SLC30A2 | Homo sapiens | Q9BRI3 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | LY6G6C | Homo sapiens | O95867 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | LY6G6C | Homo sapiens | O95867 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ERP29 | Homo sapiens | P30040 | 32296183 | |
|
Intra
|
SLC38A7 | Q9NVC3 | ERP29 | Homo sapiens | P30040 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction
関連疾患
| Diseases | Alias | |
|---|---|---|
| Triple-Receptor Negative Breast Cancer |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| 製品番号 | 製品名 |
製品効果
|
純度 |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS13225 | SLC38A7 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Bos taurus | SLC38A7 | VGNC | VGNC:34854 |
| Felis catus | SLC38A7 | VGNC | VGNC:65350 |
| Macaca mulatta | SLC38A7 | VGNC | VGNC:77570 |
| Mus musculus | SLC38A7 | MGD | MGI:2679005 |
| Rattus norvegicus | SLC38A7 | RGD | RGD:1303268 |
| Canis familiaris | SLC38A7 | VGNC | VGNC:46397 |
| Others | SLC38A7 | NCBI |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service