Vdac2 - voltage-dependent anion channel 2 Gene

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 83531

Summary

Predicted to enable several functions, including Cholesterol binding activity; phosphatidylcholine binding activity; and voltage-gated anion channel activity. Predicted to be involved in several processes, including binding activity of sperm to zona pellucida; mitochondrial outer membrane permeabilization; and negative regulation of intrinsic apoptotic signaling pathway. Located in mitochondrion and synaptic vesicle. Used to study Myocardial Infarction and visual Epilepsy. Biomarker of temporal lobe Epilepsy. Orthologous to human VDAC2 (voltage dependent anion channel 2). [provided by Alliance of Genome Resources, Apr 2022]

Vdac2 Products (1)

mRNA Protein Name
NM_031354.1 NP_112644.1 voltage-dependent anion-selective channel protein 2

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence 参考文献 由来
located in synaptic vesicle IDA
IDA: Inferred from direct assay
19187093 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent anion-selective channel protein 2

  • B36-VDAC

  • VDAC-2

  • outer mitochondrial membrane protein porin 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-15763 Erastin Inhibitor 99.91% Unkown
HY-128777 WEHI-9625 Inhibitor 99.46% Unkown
HY-172262 WEHI-3773 Ligand 99.89% Unkown
HY-181529 NCATS-SM0225 Ligand / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Vdac2 NCBI NCBI:7417