GSK2647544
Based on 1 Customer Validation
GSK2647544 is an orally available, selective inhibitor of Lp-PLA2. Lipoprotein-associated phospholipase (Lp-PLA2) is a calcium-independent phospholipase A2 with proinflammatory activities that is primarily secreted by monocyte-derived macrophages.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.50%
- CAS 番号: 1380426-95-8
- 分子式: C24H18ClF3N4O3
- 分子量:502.87
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Immunology/Inflammation Compound Library
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Metabolism/Protease Compound Library
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Clinical Compound Library
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Anti-Cardiovascular Disease Compound Library
HY-L046
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Orally Active Compound Library
HY-L061
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Lipid Metabolism Compound Library
HY-L091
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Heterocyclic Compound Library
HY-L138
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Metabolic Enzyme Compound Library
HY-L146
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Highly Selective Inhibitors Library
HY-L158
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Macrophage Related Compound Library
HY-L174
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Clinical Compound Library Plus
HY-L026P
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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Phospholipase アイソフォーム固有の製品をすべて表示
More
生物活性
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 1380426-95-8
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性状 Solid
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分子量 502.87
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分子式 C24H18ClF3N4O3
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Color White to off-white
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SMILES
O=C1NC(OCCC2=CC=C(C=C2)OC3=CC=C(C(C(F)(F)F)=C3)Cl)=NC=C1CC4=CN=CN=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 100 mg/mL (198.86 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9886 mL | 9.9429 mL | 19.8859 mL | 49.7146 mL |
| 5 mM | 0.3977 mL | 1.9886 mL | 3.9772 mL | 9.9429 mL | |
| 10 mM | 0.1989 mL | 0.9943 mL | 1.9886 mL | 4.9715 mL | |
| 15 mM | 0.1326 mL | 0.6629 mL | 1.3257 mL | 3.3143 mL | |
| 20 mM | 0.0994 mL | 0.4971 mL | 0.9943 mL | 2.4857 mL | |
| 25 mM | 0.0795 mL | 0.3977 mL | 0.7954 mL | 1.9886 mL | |
| 30 mM | 0.0663 mL | 0.3314 mL | 0.6629 mL | 1.6572 mL | |
| 40 mM | 0.0497 mL | 0.2486 mL | 0.4971 mL | 1.2429 mL | |
| 50 mM | 0.0398 mL | 0.1989 mL | 0.3977 mL | 0.9943 mL | |
| 60 mM | 0.0331 mL | 0.1657 mL | 0.3314 mL | 0.8286 mL | |
| 80 mM | 0.0249 mL | 0.1243 mL | 0.2486 mL | 0.6214 mL | |
| 100 mM | 0.0199 mL | 0.0994 mL | 0.1989 mL | 0.4971 mL |
GSK2647544 関連分類
HY-145653 関連分類
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