1380426-95-8
1380426-95-8
Chemical Structure
GSK2647544
- CAS No.: 1380426-95-8
- Formula:C24H18ClF3N4O3
- Molecular Weight:502.87
IUPAC Name: 2-(4-(4-chloro-3-(trifluoromethyl)phenoxy)phenethoxy)-5-(pyrimidin-5-ylmethyl)pyrimidin-4(3H)-one
InChIKey: DRACNSAQZFZUKW-UHFFFAOYSA-N
SMILES: O=C1NC(OCCC2=CC=C(C=C2)OC3=CC=C(C(C(F)(F)F)=C3)Cl)=NC=C1CC4=CN=CN=C4
Biological Activity: GSK2647544 is an orally available, selective inhibitor of Lp-PLA2. Lipoprotein-associated phospholipase (Lp-PLA2) is a calcium-independent phospholipase A2 with proinflammatory activities that is primarily secreted by monocyte-derived macrophages[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK2647544 | 99.50% | GSK2647544 is an orally available, selective inhibitor of Lp-PLA2. Lipoprotein-associated phospholipase (Lp-PLA2) is a calcium-independent phospholipase A2 with proinflammatory activities that is primarily secreted by monocyte-derived macrophages. | ||||||||||||||||||||
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References
Keywords
