m-PEG13-NHS ester
Based on 1 Customer Validation
m-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.0%
- CAS 番号: 3063847-98-0
- 分子式: C32H59NO17
- 分子量:729.81
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保管条件:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3063847-98-0
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性状 Oil
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分子量 729.81
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分子式 C32H59NO17
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Color Colorless to off-white
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SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
DMSO : 100 mg/mL (137.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3702 mL | 6.8511 mL | 13.7022 mL | 34.2555 mL |
| 5 mM | 0.2740 mL | 1.3702 mL | 2.7404 mL | 6.8511 mL | |
| 10 mM | 0.1370 mL | 0.6851 mL | 1.3702 mL | 3.4255 mL | |
| 15 mM | 0.0913 mL | 0.4567 mL | 0.9135 mL | 2.2837 mL | |
| 20 mM | 0.0685 mL | 0.3426 mL | 0.6851 mL | 1.7128 mL | |
| 25 mM | 0.0548 mL | 0.2740 mL | 0.5481 mL | 1.3702 mL | |
| 30 mM | 0.0457 mL | 0.2284 mL | 0.4567 mL | 1.1418 mL | |
| 40 mM | 0.0343 mL | 0.1713 mL | 0.3426 mL | 0.8564 mL | |
| 50 mM | 0.0274 mL | 0.1370 mL | 0.2740 mL | 0.6851 mL | |
| 60 mM | 0.0228 mL | 0.1142 mL | 0.2284 mL | 0.5709 mL | |
| 80 mM | 0.0171 mL | 0.0856 mL | 0.1713 mL | 0.4282 mL | |
| 100 mM | 0.0137 mL | 0.0685 mL | 0.1370 mL | 0.3426 mL |