NVC-422
NVC-422 is a N-chlorotaurine analog, virucidal agent, antibacterial agent. NVC-422 exhibits virucidal activity against Ad5 by the oxidative inactivation of key viral proteins (fiber and hexon), leading to the loss of viral integrity and infectivity. NVC-422 is shown to be highly effective in killing all microbial strains tested, including antibiotic-resistant S. aureus and E. faecium. NVC-422 can be used in the research of adenoviral conjunctivitis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 846056-87-9
- 分子式: C4H9Cl2NO3S
- 分子量:222.09
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 846056-87-9
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分子量 222.09
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分子式 C4H9Cl2NO3S
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SMILES
CC(C)(N(Cl)Cl)CS(=O)(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Yoon J, et al. Virucidal mechanism of action of NVC-422, a novel antimicrobial drug for the treatment of adenoviral conjunctivitis. Antiviral Res. 2011 Dec;92(3):470-8. [Content Brief]
[2]. Wang L, et al. Chemical characterization and biological properties of NVC-422, a novel, stable N-chlorotaurine analog. Antimicrob Agents Chemother. 2011 Jun;55(6):2688-92. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)