Nystatin A1
Nystatin A1 is a polyene macrolide antifungal antibiotic that can be isolated from Streptomyces noursei. Nystatin A1 binds to ergosterol on the fungal cell membrane, increasing the permeability of the cell membrane and causing leakage of cell contents, thereby inhibiting the growth and reproduction of fungi.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 34786-70-4
- 分子式: C47H75NO17
- 分子量:926.09
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEp-2 | CC50 |
13.6 μg/mL
Compound: Nystatin
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Cytotoxicity against human HEp-2 cells assessed as reduction in cell viability incubated for 40 to 60 mins by resazurin dye based assay
Cytotoxicity against human HEp-2 cells assessed as reduction in cell viability incubated for 40 to 60 mins by resazurin dye based assay
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[PMID: 35178173] |
| HEp-2 | CC50 |
78 units/mg
Compound: Nystatin
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Cytotoxicity against human HEp-2 cells assessed as reduction in cell viability incubated for 40 to 60 mins by resazurin dye based assay
Cytotoxicity against human HEp-2 cells assessed as reduction in cell viability incubated for 40 to 60 mins by resazurin dye based assay
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[PMID: 35178173] |
| WI-38 | CC50 |
48.56 μM
Compound: Nystatin
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Cytotoxicity against human WI38 cells assessed as reduction in cellular DNA level preincubated for 2 hrs before viral infection measured after 7 days by real time PCR assay
Cytotoxicity against human WI38 cells assessed as reduction in cellular DNA level preincubated for 2 hrs before viral infection measured after 7 days by real time PCR assay
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[PMID: 17893158] |
| WI-38 | EC50 |
9.81 μM
Compound: Nystatin
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Antiviral activity against BKV Gardner ATCC VR837 infected in human WI38 cells assessed as reduction in viral DNA level preincubated for 2 hrs before viral infection measured after 7 days by real time PCR assay
Antiviral activity against BKV Gardner ATCC VR837 infected in human WI38 cells assessed as reduction in viral DNA level preincubated for 2 hrs before viral infection measured after 7 days by real time PCR assay
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[PMID: 17893158] |
化学情報
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CAS 番号 34786-70-4
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分子量 926.09
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分子式 C47H75NO17
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SMILES
O=C([C@H]1[C@]2([H])C[C@@H](O[C@H]3[C@@H](O)[C@@H](N)[C@H](O)[C@@H](C)O3)/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O2)(O)C[C@@H]1O)=O)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Nystatin A1 関連分類
HY-159666 関連分類
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