BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport

  • Antimicrob Agents Chemother. 2007 Dec;51(12):4492-4. doi: 10.1128/AAC.00843-07.
Parmjeet Randhawa  1 ,  Noush Afarin Farasati ,  Yuchen Huang
Affiliations
  • 1. Division of Transplantation Pathology, Department of Pathology, University of Pittsburgh, UPMC-Montefiore Hospital, Pittsburgh, PA 15213, USA. [email protected]
PMID: 17893158 DOI: 10.1128/AAC.00843-07
Abstract

BK virus is an important pathogen in kidney transplant recipients. In vitro studies demonstrated slight Antiviral activity for chloroquine and nystatin. A sialic acid derivative, BTB11968, was identified as a lead compound for further development.