(RS)-PPG (Standard)
(RS)-PPG (Standard) is the analytical standard of (RS)-PPG (HY-107514). This product is intended for research and analytical applications. (RS)-PPG is a potent and selective agonist for group III mGluRs. The EC50s of 5.2 μM, 4.7 μM, 185 μM, and 0.2 μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively. Anticonvulsive and neuroprotective activity.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 120667-15-4
- 分子式: C8H10NO5P
- 分子量:231.14
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
EC50: 5.2 μM (hmGluR4a), 4.7 μM (hmGluR6), 185 μM (hmGluR7b), and 0.2 μM (hmGluR8a)[1]
化学情報
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CAS 番号 120667-15-4
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分子量 231.14
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分子式 C8H10NO5P
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SMILES
O=C(O)C(N)C1=CC=C(P(O)(O)=O)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Gasparini F, et al. (R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo. J Pharmacol Exp Ther. 1999 Jun;289(3):1678-87. [Content Brief]
[2]. Zhao L, et al. Activation of group III metabotropic glutamate receptor reduces intracellular calcium in beta-amyloid peptide [31-35]-treated cortical neurons. Neurotox Res. 2009 Aug;16(2):174-83. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
(RS)-PPG (Standard) 関連分類
HY-107514R 関連分類
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