69 Results for "

LAMP

" in MedChemExpress (MCE) Product Catalog:
Products (69)

69 Results for "LAMP" in MCE Product Catalog:

8
8 Publications Verification
製品番号: HY-134923
CAS 番号: 2412270-22-3
純度:  99.98%
Target:  

Autophagy

研究分野:  

Neurological Disease

CA77.1 is a potent, brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics. CA77.1 is a derivative of AR7 (HY-101106) and can increase the expression of the lysosomal receptor LAMP2A in?lysosomes. CA77.1 improves behavior and neuropathology in PS19 mice model and can be used for alzheimer's?disease research .
loading...
    loading...
7
7 Cited Publications
製品番号: HY-112483
CAS 番号: 1798331-92-6
純度:  99.48%
Target:  

Autophagy

研究分野:  

Cancer

QX77 is a chaperone-mediated autophagy (CMA) activator and upregulates LAMP2A expression in vitro. QX77 induces Rab11 upregulation, rescues Rab11 down-regulation and trafficking deficiency in cystinotic cells . QX77 can impede self-renewal and promote differentiation of ES cells .
loading...
    loading...
1
1 Cited Publications
製品番号: HY-P80206
別名: CD107 antigen like family member A antibody; CD107 antigen-like family member A antibody; CD107a antibody; CD107a antigen antibody; LAMP 1 antibody; LAMP-1 antibody; LAMP1 antibody; LAMP1_HUMAN antibody; LAMPA antibody; LGP120 antibody; lgpA antibody; Lysosomal membrane glycoprotein 120KD antibody; Lysosomal Associated Membrane Protein 1 antibody; Lysosome associated membrane glycoprotein 1 antibody; Lysosome-associated membrane glycoprotein 1 antibody; Lysosome-associated membrane protein 1 antibody; OTTHUMP00000040663 antibody;

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human

loading...
    loading...
1
1 Cited Publications
製品番号: HY-P72525
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: LAMP2; LAMP-2; Lysosome Associated Membrane Protein 2; LGP-96; Lysosomal Associated Membrane Protein 2; Lysosome-Associated Membrane Protein 2; Lysosome-Associated Membrane Glycoprotein 2; CD107b Antigen; CD107 Antigen-Like Family Member B; LGP110; CD107b
Species:  
Human
Source:  
HEK293
loading...
    loading...
製品番号: HY-W110910
CAS 番号: 1787-61-7
Eriochrome black T, Indicator is a complexing agent for metal ions (e.g., Ca 2+, Mg 2+) and is used as an indicator in complexometric titrations. Eriochrome black T, Indicator forms colored complexes with metal ions through covalent coordination bonds, and indicates the endpoint of the titration by color change. Eriochrome black T, Indicator can be used as an anionic azo dye in photocatalytic degradation studies to evaluate the performance of photocatalysts. The reaction solution of Eriochrome black T, Indicator combined with Mg 2+ is initially purple. During loop-mediated isothermal amplification (LAMP), the color changes from purple to sky blue due to the consumption of Mg 2+ by the formation of magnesium pyrophosphate, indicating a positive reaction. The optimal concentration of Eriochrome black T, Indicator in LAMP is 60 μM, and the detection limit for Mycobacterium tuberculosis is 1 pg DNA/reaction .
loading...
    loading...
製品番号: HY-W075766
CAS 番号: 10028-18-9
別名: Nickel difluoride
Nickel(II) fluoride (Nickel difluoride) is a fluorinating agent and catalyst suitable for surface treatment of aluminum profiles and the production of inks, fluorescent lamps, and organic synthesis. Nickel(II) fluoride is a kind of biological materials or organic compounds that are widely used in life science research .
loading...
    loading...
製品番号: HY-D0485
CAS 番号: 12224-02-1
Target:  

Fluorescent Dye

研究分野:  

Others

Fluorescent brightener 24 is a stilbene-type fluorescent brightener and fading regulator .
loading...
    loading...
製品番号: HY-P991082
別名: SAR-428926 antibody

研究分野:  

Cancer

Anti-LAMP1/CD107a Antibody (SAR-428926 antibody) is an anti-LAMP1 humanized monoclonal antibody. Anti-LAMP1/CD107a Antibody can be used for the antibody part of SAR-428926. Antibody Anti-LAMP1/CD107a Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001) .
loading...
    loading...
製品番号: HY-RS07511
研究分野:  

Others

LAMP3 Human Pre-designed siRNA Set A contains three designed siRNAs for LAMP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-169363
研究分野:  

Cancer

PD-L1 degrader-2 (Compound B3) is an orally active AUTAC degrader, that degrades PD-L1 through autophagy-lysosome pathway with a DC50 of 0.5 μM. PD-L1 degrader-2 exhibits inhibitory activity against PD-1/PD-L1 interaction with an IC50 of 22.8 nM. PD-L1 degrader-2 upregulates the expressions of Atg9b, Lamp1 and Mitf, and activates the autophagy lysosome system. PD-L1 degrader- exhibits antitumor efficacy in CT26 mouse model . (Pink: autophagy-lysosome activator (HY-159894); Black: linker (HY-W015088); Blue: PD-L1 ligand (HY-169365))
loading...
    loading...
製品番号: HY-P991510

Target:  

TNF Receptor

研究分野:  

Cancer

CDX-1140 is a fully human IgG monoclonal antibody and CD40 agonist, with a Kd value of 0.01 nM against human targets. The epitope of CDX-1140 locates at CD40 CRD1 and avoids the CD40L binding site. It activates DCs and B cells, drives NF-κB reporter gene activation, exhibits agonist activity independent of FcR cross-linking, and shows a synergistic effect with recombinant CD40L . CDX-1140 does not induce systemic cytokine release, exerts direct and immune-mediated anti-tumor activity in tumor xenografts, and has favorable safety profiles. When used as a local vaccine adjuvant in combination with 6MHP+mBRAF+poly-ICLC, CDX-1140 increases the number of DC-LAMP + DCs and induces Th1 CD4 + responses in high-risk melanoma. CDX-1140 can be used in studies related to B-cell lymphoma, bladder cancer and high-risk melanoma .
loading...
    loading...
製品番号: HY-RS07509
研究分野:  

Others

LAMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for LAMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-RS07510
研究分野:  

Others

LAMP2 Human Pre-designed siRNA Set A contains three designed siRNAs for LAMP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-RS07512
研究分野:  

Others

LAMP5 Human Pre-designed siRNA Set A contains three designed siRNAs for LAMP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-RS17112
研究分野:  

Others

Lamp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lamp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-RS17172
研究分野:  

Others

Lamp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lamp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-RS23557
研究分野:  

Others

Lamp2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lamp2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-RS24235
研究分野:  

Others

Lamp3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lamp3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-RS25013
研究分野:  

Others

Lamp5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lamp5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-RS17768
研究分野:  

Others

Lamp3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lamp3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...