TD-6450
TD-6450 (Compound 51) is an orally active HCV 1A inhibitor. TD-6450 inhibits the pan-genotypic nonstructural protein 5A (NS5A). TD-6450 can be used for research on diseases such as hepatitis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1374883-22-3
- 分子式: C41H48F3N9O6
- 分子量:819.87
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
-
CAS 番号 1374883-22-3
-
分子量 819.87
-
分子式 C41H48F3N9O6
-
SMILES
COC(N[C@@H](C(C)C)C(N1[C@H](C(N2)=NC=C2C(C=C3)=CC=C3C4=C(OC(F)(F)F)C=C(NC(C5=CN=C(C=C5)N6C[C@@H](N(C[C@H]6C)C(NC)=O)C)=O)C=C4)CCC1)=O)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Belema M, et al. Discovery and development of hepatitis C virus NS5A replication complex inhibitors. J Med Chem. 2014 Mar 13;57(5):1643-72. [Content Brief]
[2]. Carucci M, et al. Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening. Nat Commun. 2023 Apr 7;14(1):1951. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)