Way 100252
Way 100252 is a presynaptic GABA autoreceptor agonist. Way 100252 exerts its effect by inhibiting GABA release, and it suppresses GABA release induced by K+, Ca2+, Ouabain (HY-B1457) and electrical stimulation, with a more potent inhibitory effect on electrically evoked release. Way 100252 is used for studies related to GABAergic neurotransmission.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 129041-16-3
- 分子式: C26H25NO2
- 分子量:383.48
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
Way 100252 dose-dependently inhibits the release of [3H] GABA evoked by various stimuli in cross-cut rat cerebral cortical slices, with pD2 values of 5.8 (Ca2+), 7.4 (K+), 6.3 (electrical stimulation) and 6.0 (Ouabain (HY-B1457)) for different stimuli, respectively, and the maximum inhibitory effect ranges from 40% to 90%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 129041-16-3
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分子量 383.48
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分子式 C26H25NO2
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SMILES
O=C(CCCN(CC1=C2C=CC=CC2=CC=C1)CC3=C4C=CC=CC4=CC=C3)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Way 100252 関連分類
HY-116484 関連分類
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