Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
GDNF Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "GDNF Receptor" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
BT18 is a molecule mimic with function similar to glial cell line-derived neurotrophic factor (GDNF) . BT18 shows an effect on GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function .
Cat. No.: HY-136832
CAS No.: 110514-35-7
Research Areas:
Noribogaine hydrochloride is an orally active, blood-brain barrier permeable SERT inhibitor (IC50=50-300 nM) and hERG channel blocker. Noribogaine hydrochloride enhances serotonergic transmission, activates the κ-opioid receptor (OPRK) G protein signaling pathway and inhibits β-arrestin recruitment. Meanwhile, Noribogaine hydrochloride blocks the μ-opioid receptor (OPRM) signaling pathway as well as ion channels associated with cardiac repolarization. Noribogaine hydrochloride induces neuritogenesis, upregulates GDNF mRNA expression, and modulates opioid tolerance. Noribogaine hydrochloride reduces alcohol-seeking behavior in experimental animals, and is widely used in studies related to depression, addiction, alcoholism, and cardiotoxicity .
Cat. No.: HY-163840
Target:
Research Areas:
GFRα2/3-IN-1 (Compound 16) is a selective GFRα2/3 inhibitor with IC50 values of 0.1 and 0.2 μM for GFRα2 and GFRα3, respectively. GFRα2 is a glial cell line-derived neurotrophic factor (GDNF) receptor related to GFRα1, GFRα2/3-IN-1 can be used for pain and itch research .
Cat. No.: HY-111969R
CAS No.: 924811-53-0
Target:
Research Areas:
BT18 (Standard) is the analytical standard of BT18 (HY-111969). This product is intended for research and analytical applications. BT18 is a molecule mimic with function similar to glial cell line-derived neurotrophic factor (GDNF) . BT18 shows an effect on GDNF family receptor GFRα1 and RET receptor tyrosine Kinase RetA function .
Cat. No.: HY-P77373
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA3; GFR-Alpha-3; GDNF Family Receptor Alpha 3; GFRa-3; GDNF Family Receptor Alpha-3; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha-3; GDNF Receptor Alpha-3; GPI-Linked Receptor; GDNFR-Alpha-3; GDNFR3
Cat. No.: HY-P76951
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: GFRA3; GFR-Alpha-3; GDNF Family Receptor Alpha 3; GFRa-3; GDNF Family Receptor Alpha-3; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha-3; GDNF Receptor Alpha-3; GPI-Linked Receptor; GDNFR-Alpha-3; GDNFR3
Cat. No.: HY-P76952
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: GFRA3; GFR-Alpha-3; GDNF Family Receptor Alpha 3; GFRa-3; GDNF Family Receptor Alpha-3; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha-3; GDNF Receptor Alpha-3; GPI-Linked Receptor; GDNFR-Alpha-3; GDNFR3
Cat. No.: HY-P77372
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: GFRA3; GFR-Alpha-3; GDNF Family Receptor Alpha 3; GFRa-3; GDNF Family Receptor Alpha-3; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha-3; GDNF Receptor Alpha-3; GPI-Linked Receptor; GDNFR-Alpha-3; GDNFR3
Cat. No.: HY-P702624
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRAL; GRAL; Prev. C6orf144; Chromosome 6 Open Reading Frame 144; BA360D14.1; IVFI9356; UNQ9356; GDNF Family Receptor Alpha Like; GDNF Family Receptor Alpha-Like
Cat. No.: HY-P704308
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRAL; GRAL; Prev. C6orf144; Chromosome 6 Open Reading Frame 144; BA360D14.1; IVFI9356; UNQ9356; GDNF Family Receptor Alpha Like; GDNF Family Receptor Alpha-Like
Cat. No.: HY-P704634
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GFRAL; GRAL; Prev. C6orf144; Chromosome 6 Open Reading Frame 144; BA360D14.1; IVFI9356; UNQ9356; GDNF Family Receptor Alpha Like; GDNF Family Receptor Alpha-Like
Cat. No.: HY-P70192
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA2; RET Ligand 2; GDNF Family Receptor Alpha 2; GDNFR-Beta; GDNFRB; NTNR-Alpha; RETL2; Glial Cell Line Derived Neurotrophic Factor Receptor, Beta; TRNR2; PI-Linked Cell-Surface Accessory Protein; GDNF Family Receptor Alpha-2; TRN Receptor, GPI-Anchored
Cat. No.: HY-P76950
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA2; RET Ligand 2; GDNF Family Receptor Alpha 2; GDNFR-Beta; GDNFRB; NTNR-Alpha; RETL2; Glial Cell Line Derived Neurotrophic Factor Receptor, Beta; TRNR2; PI-Linked Cell-Surface Accessory Protein; GDNF Family Receptor Alpha-2; TRN Receptor, GPI-Anchored
Cat. No.: HY-P700728
Purity: ≥ 95%, as determined by reducing Bis-Tris PAGE.
Synonyms: GFRAL; GRAL; Prev. C6orf144; Chromosome 6 Open Reading Frame 144; BA360D14.1; IVFI9356; UNQ9356; GDNF Family Receptor Alpha Like; GDNF Family Receptor Alpha-Like
Cat. No.: HY-P77683
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GFRAL; GRAL; Prev. C6orf144; Chromosome 6 Open Reading Frame 144; BA360D14.1; IVFI9356; UNQ9356; GDNF Family Receptor Alpha Like; GDNF Family Receptor Alpha-Like
Species:
Source:
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
