Neuroprotective agent 15
Neuroprotective agent 15 (Compound 3e) is a neuroprotective agent. Neuroprotective agent 15 is a selective butyrylcholinesterase (BChE) inhibitor, with IC50 values of 2.6 and 114.3 μM for BChE and AChE respectively. Neuroprotective agent 15 has cannabinoid CB2 receptor (CB2 receptor) agonistic activity. Neuroprotective agent 15 can reduce cell death, LDH release and Caspase-3/7 activity, and inhibit apoptosis. Neuroprotective agent 15 can reduce the formation of superoxide free radicals, maintain cell morphology, and significantly lower oxidative stress levels. Neuroprotective agent 15 can be used in the research of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.
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- CAS No.: 2476614-40-9
- 화학식: C20H24N6O
- 분자량:364.44
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Caspase Isoforms
More
Biological Activity
|
CB2 |
BChE 2.6 μM (IC50) |
AChE 114.3 μM (IC50) |
Caspase 3 |
Caspase-7 |
Chemical Information
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CAS No. 2476614-40-9
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분자량 364.44
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화학식 C20H24N6O
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SMILES
OC1=CC=C(CN2C3=NC(N4CCCC4)=NC(N5CCCC5)=C3N=C2)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)