1. Apoptosis
  2. Apoptosis
  3. Lepidozin G

Lepidozin G inhibits the growth of a panel of cancer cell lines with IC50 values ranging from 4.2 ± 0.2 to 5.7 ± 0.5 μM. Lepidozin G induces PC-3 cell death via mitochondrial-related apoptosis.

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Lepidozin G

Lepidozin G Estructura química

No. CAS : 2869125-43-7

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Descripciòn

Lepidozin G inhibits the growth of a panel of cancer cell lines with IC50 values ranging from 4.2 ± 0.2 to 5.7 ± 0.5 μM. Lepidozin G induces PC-3 cell death via mitochondrial-related apoptosis.

Cellular Effect
Cell Line Type Value Description References
A549 IC50
4.4 μM
Compound: 7
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
[PMID: 34797067]
NCI-H3255 IC50
5.7 μM
Compound: 7
Cytotoxicity against human NCI-H3255 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H3255 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
[PMID: 34797067]
NCI-H446 IC50
5 μM
Compound: 7
Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
[PMID: 34797067]
PC-3 IC50
4.2 μM
Compound: 7
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
[PMID: 34797067]
Peso molecular

472.70

Fòrmula

C30H48O4

No. CAS
SMILES

CC(C(CC[C@@H](C)[C@@]1([H])[C@H](O)C[C@@]2(C)[C@]3([H])CC[C@]4([H])[C@@](CC[C@H](O)C4(C)C)(O)CC3=CC[C@@]21C)=O)=C

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Lepidozin G Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Lepidozin G
Cat. No.:
HY-141863
Cantidad:
MCE Japan Authorized Agent: