2. Neuronal Signaling
  3. Monoamine Oxidase
  4. LSD1-IN-2

LSD1-IN-2 is a LSD1 inhibitor with an IC50 of 0.5 μM. LSD1-IN-2 increases the levels of monomethylated and dimethylated histone H3 lysine 4 (H3K4me1/2) in cells. LSD1-IN-2 reactivates epigenetically silenced tumor suppressor genes. LSD1-IN-2 can be used in the research of colon cancer.

For research use only. We do not sell to patients.

LSD1-IN-2

LSD1-IN-2 Chemical Structure

CAS No. : 927019-63-4

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LSD1-IN-2 Related Antibodies

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Description

LSD1-IN-2 is a LSD1 inhibitor with an IC50 of 0.5 μM. LSD1-IN-2 increases the levels of monomethylated and dimethylated histone H3 lysine 4 (H3K4me1/2) in cells. LSD1-IN-2 reactivates epigenetically silenced tumor suppressor genes. LSD1-IN-2 can be used in the research of colon cancer[1].

IC50 & Target[1]

LSD1

0.5 μM (IC50)

In Vitro

LSD1-IN-2 (Compound 39) potently inhibits LSD1 with an IC50 of 0.5 μM[1].
LSD1-IN-2 (0.5-10 μM) induces dose-dependent increases in H3K4me1/2 levels and tumor suppressor gene re-expression in HCT-116 colon cancer cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

LSD1-IN-2 Related Antibodies
Molecular Weight

328.51

Formula

C15H36N8
CAS No.
SMILES

N(=C(NC)NC)CCCNCCCNCCCN=C(NC)NC
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Purity & Documentation
References
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LSD1-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LSD1-IN-2927019-63-4Monoamine OxidaseMAOHCT-116 colon cancer cellsLSD1/KDM1Alysine-specific demethylase 1colon cancerH3K4me1/2tumor suppressor geneshistone H3 lysine 4Inhibitorinhibitorinhibit

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