927019-63-4
Chemical Structure
LSD1-IN-2
- CAS No.: 927019-63-4
- Formula:C15H36N8
- Molecular Weight:328.51
IUPAC Name: 2,2'-((propane-1,3-diylbis(azanediyl))bis(propane-3,1-diyl))bis(1,3-dimethylguanidine)
InChIKey: UECHIPVWNJCQJH-UHFFFAOYSA-N
SMILES: N(=C(NC)NC)CCCNCCCNCCCN=C(NC)NC
Biological Activity: LSD1-IN-2 is a LSD1 inhibitor with an IC50 of 0.5 μM. LSD1-IN-2 increases the levels of monomethylated and dimethylated histone H3 lysine 4 (H3K4me1/2) in cells. LSD1-IN-2 reactivates epigenetically silenced tumor suppressor genes. LSD1-IN-2 can be used in the research of colon cancer[1].
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LSD1-IN-2 | LSD1-IN-2 is a LSD1 inhibitor with an IC50 of 0.5 μM. LSD1-IN-2 increases the levels of monomethylated and dimethylated histone H3 lysine 4 (H3K4me1/2) in cells. LSD1-IN-2 reactivates epigenetically silenced tumor suppressor genes. LSD1-IN-2 can be used in the research of colon cancer. | |||||||||||||||||||||
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Keywords