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N-Oxalylglycine (N-Oxaloglycine) is a broad-spectrum 2-oxoglutarate oxygenase inhibitor. N-Oxalylglycine can be used in studies on the hypoxic response and chromatin modifications in animals.

For research use only. We do not sell to patients.

N-Oxalylglycine Chemical Structure

N-Oxalylglycine Chemical Structure

CAS No. : 5262-39-5

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Based on 1 publication(s) in Google Scholar

N-Oxalylglycine Related Antibodies

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Description

N-Oxalylglycine (N-Oxaloglycine) is a broad-spectrum 2-oxoglutarate oxygenase inhibitor. N-Oxalylglycine can be used in studies on the hypoxic response and chromatin modifications in animals[1][1].

Molecular Weight

147.09

Formula

C4H5NO5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CNC(C(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (679.86 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.7986 mL 33.9928 mL 67.9856 mL
5 mM 1.3597 mL 6.7986 mL 13.5971 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.7986 mL 33.9928 mL 67.9856 mL 169.9640 mL
5 mM 1.3597 mL 6.7986 mL 13.5971 mL 33.9928 mL
10 mM 0.6799 mL 3.3993 mL 6.7986 mL 16.9964 mL
15 mM 0.4532 mL 2.2662 mL 4.5324 mL 11.3309 mL
20 mM 0.3399 mL 1.6996 mL 3.3993 mL 8.4982 mL
25 mM 0.2719 mL 1.3597 mL 2.7194 mL 6.7986 mL
30 mM 0.2266 mL 1.1331 mL 2.2662 mL 5.6655 mL
40 mM 0.1700 mL 0.8498 mL 1.6996 mL 4.2491 mL
50 mM 0.1360 mL 0.6799 mL 1.3597 mL 3.3993 mL
60 mM 0.1133 mL 0.5665 mL 1.1331 mL 2.8327 mL
80 mM 0.0850 mL 0.4249 mL 0.8498 mL 2.1245 mL
100 mM 0.0680 mL 0.3399 mL 0.6799 mL 1.6996 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N-Oxalylglycine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Oxalylglycine5262-39-5N-OxaloglycineOthers2-oxoglutarate oxygenase inhibitorInhibitorinhibitorinhibit

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