1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease
  3. Nafamostat mesylate

Nafamostat mesylate (Synonyms: FUT-175)

Cat. No.: HY-B0190A Purity: 99.97%
Handling Instructions

Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat mesylate supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis.

For research use only. We do not sell to patients.

Nafamostat mesylate Chemical Structure

Nafamostat mesylate Chemical Structure

CAS No. : 82956-11-4

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
10 mg USD 50 In-stock
Estimated Time of Arrival: December 31
50 mg USD 100 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Other Forms of Nafamostat mesylate:

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Description

Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat mesylate supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis[1][2][3].

IC50 & Target

Serine Protease[1][2].
Granzyme[3].

Clinical Trial
Storage

4°C, protect from light

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (92.66 mM; Need ultrasonic)

H2O : 33.33 mg/mL (61.77 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8533 mL 9.2665 mL 18.5329 mL
5 mM 0.3707 mL 1.8533 mL 3.7066 mL
10 mM 0.1853 mL 0.9266 mL 1.8533 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (4.63 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.63 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (4.63 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

539.58

Formula

C₂₁H₂₅N₅O₈S₂

CAS No.

82956-11-4

SMILES

CS(=O)(O)=O.O=C(OC1=CC=C2C=C(C(N)=N)C=CC2=C1)C3=CC=C(NC(N)=N)C=C3.CS(=O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Nafamostat mesylate
Cat. No.:
HY-B0190A
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Nafamostat mesylate

Cat. No.: HY-B0190A