1. Anti-infection
    Metabolic Enzyme/Protease
  2. Fungal
    Cytochrome P450
  3. Quilseconazole

Quilseconazole (Synonyms: VT-1129)

Cat. No.: HY-109040
Handling Instructions

Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes.

For research use only. We do not sell to patients.

Quilseconazole Chemical Structure

Quilseconazole Chemical Structure

CAS No. : 1340593-70-5

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Description

Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes[1].

IC50 & Target

Fungal, Cyp51[1]

Molecular Weight

513.37

Formula

C₂₂H₁₄F₇N₅O₂

CAS No.

1340593-70-5

SMILES

O[[email protected]@](CN1C=NN=N1)(C(C=CC(F)=C2)=C2F)C(F)(C3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)C=N3)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Quilseconazole
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HY-109040
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