CD68 Protein, Human (sf9, His)

CD68 protein is essential for phagocytic activities in tissue macrophages, including lysosomal metabolism and interactions with cells and pathogens. It binds to lectins or selectins, aiding targeted migration of specific macrophage subsets. CD68's rapid recirculation from endosomes and lysosomes to the plasma membrane allows macrophages to crawl or interact with selectin-bearing substrates and other cells. CD68 Protein, Human (sf9, His) is the recombinant human-derived CD68 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of CD68 Protein, Human (sf9, His) is 319 a.a., with molecular weight of ~68 kDa.

CD68 protein is thought to play a crucial role in various phagocytic activities carried out by tissue macrophages, encompassing intracellular lysosomal metabolism as well as extracellular interactions with cells and pathogens. It has the ability to bind to tissue- and organ-specific lectins or selectins, facilitating the targeted migration of specific macrophage subsets to particular sites. The rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane enables macrophages to crawl over selectin-bearing substrates or interact with other cells.

Human

Sf9 insect cells

C-His

P34810 (M1-S319)

968  [NCBI]

Approximately 68 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.