1 Result for "

1603833-56-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1603833-56-2" in MCE Product Catalog:

Cat. No.: HY-171349
CAS No.: 1603833-56-2
Target:  

γ-secretase Amyloid-β

Research Areas:  

Neurological Disease

Amyloid-β-IN-3 (EX.113) is a selective γ-secretase inhibitor. Amyloid-β-IN-3 inhibits Aβ42 secretion in H4 cells with an EC50 value of 148 nM. Amyloid-β-IN-3 regulates the γ-secretase catalytic activity to decrease Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. Amyloid-β-IN-3 is promising for research of Alzheimer's disease (AD) .
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