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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
62 Results for "
3r1
" in MedChemExpress (MCE) Product Catalog:
Products (62)
62 Results for "3r1" in MCE Product Catalog:
45
45 Publications Verification
Synonyms: DTT; rel-(2R,3R)-1,4-Dimercapto-2,3-butanediol
8
8 Cited Publications
Cat. No.: HY-P80846
Synonyms: PIK3r1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s
4
4 Cited Publications
Cat. No.: HY-P80867
Synonyms: PIK3r1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s
1
1 Cited Publications
Category:
1
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CYM50308 (ML248) is a potent, selective and high affinity sphingosine-1-phosphate receptor 4 (S1P4-R) agonist with an EC50 of 56 nM. CYM50308 displays 37-fold more selective for S1P4-R than S1P5-R. CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM .
1
1 Cited Publications
Cat. No.: HY-P701153
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EBP50; NHERF; NHERF-1; NHERF1; NPHLOP2
Cat. No.: HY-P10849
CAS No.: 3061802-23-8
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CYM50260 is a potent and exquisitely selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonist with an EC50 of 45 nM. CYM50260 displays no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R .
Cat. No.: HY-40041
CAS No.: 163765-44-4
Cat. No.: HY-W111383
CAS No.: 193693-65-1
Synonyms: (R)-1-Fmoc-3-pyrrolidinecarboxylic acid
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Fmoc-D-β-Pro-OH ((R)-1-Fmoc-3-pyrrolidinecarboxylic acid) is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-40097
CAS No.: 147081-49-0
Cat. No.: HY-P11540
CAS No.: 2923120-30-1
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Cat. No.: HY-162774A
GRP75-IN-1 hydrochloride (compound 33) is an anti-endometrial cancer (EC) agent that induces apoptosis. GRP75-IN-1 hydrochloride reduces Ca 2+ levels in mitochondria by targeting GRP75 and disrupting its interaction with IP3R .
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H4R antagonist 1 is a potent and highly selective histamine H4 receptor (H4R) antagonist with an IC50 of 27 nM. H4R antagonist 1 does not show any noticeable binding affinity to other subtypes of histamine receptors, H1R, H2R, and H3R .
Cat. No.: HY-P3862
CAS No.: 110880-53-0
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MRE3008F20 is a highly efficient, highly selective and radioactive adenosine A3 receptor (AA3R) antagonist (Ki=1.8 nM). MRE3008F20 effectively antagonises Cl-IB-MECA-induced cAMP production in resting lymphocytes with an IC50 value of 5 nM. MRE3008F20 can be used in the study of AA3R .
Cat. No.: HY-161366
CAS No.: 3033806-03-7
OMS14 is exhibits inhibitory activity for phosphoinositide 3-kinase γ (PI3Kγ) and PIK3CD/PIK3R1, which inhibits 19% PI3Kγ and 65% PIK3CD/PIK3R1 activity at 100 μM. OMS14 exhibits anticancer efficacy in various cancer cells .
Cat. No.: HY-W590670
CAS No.: 121459-06-1
Synonyms: N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl]icosanamide
Cat. No.: HY-100617A
CAS No.: 7292-81-1
Synonyms: (RS)-4-Carboxyphenylglycine
(RS)-4CPG ((RS)-4-Carboxyphenylglycine) is a type I metabotropic glutamate receptor antagonist with activity in blocking LTP induction. In mice lacking IP3R1, (RS)-4CPG (500μM) nearly blocked long-term potentiation (LTP) induced by type I metabotropic glutamate receptor activation, with LTP of 117.6±1.7% (n = 8) in IP3R1(-/-) mice and 116.9±1.8% (n = 5) in IP3R1(+/+) mice.
Cat. No.: HY-40062
CAS No.: 928025-57-4
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(R)-1-Boc-3-propylpiperazine is a drug intermediate for synthesis of various active compounds.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
