62 Results for "

3r1

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "3r1" in MCE Product Catalog:

45
45 Publications Verification
製品番号: HY-15917
CAS 番号: 3483-12-3
別名: DTT; rel-(2R,3R)-1,4-Dimercapto-2,3-butanediol
DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-Dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond .
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8
8 Cited Publications
製品番号: HY-P80846
別名: PIK3r1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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4
4 Cited Publications
製品番号: HY-P80867
別名: PIK3r1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s

Host:  

Mouse

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
製品番号: HY-129139
CAS 番号: 111613-04-8
純度:  95.71%
Cyanidin-3-O-arabinoside is a p38 MAPK phosphorylation inhibitor. Cyanidin-3-O-arabinoside reduces the expression of VDAC1, inhibits mtROS accumulation, reverses cellular senescence, blocks excessive mitochondrial calcium influx, reduces the formation of mitochondria-associated endoplasmic reticulum membranes, and suppresses the VDAC1-IP3R1 interaction. Cyanidin-3-O-arabinoside activates hair follicle stem cell proliferation and improves the condition of slowed hair growth. Cyanidin-3-O-arabinoside is applicable to research related to colon cancer and androgenetic alopecia .
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1
1 Cited Publications
製品番号: HY-108495
CAS 番号: 1345858-76-5
純度:  ≥98.0%
別名: ML248
Target:  

LPL Receptor

研究分野:  

Cardiovascular Disease

CYM50308 (ML248) is a potent, selective and high affinity sphingosine-1-phosphate receptor 4 (S1P4-R) agonist with an EC50 of 56 nM. CYM50308 displays 37-fold more selective for S1P4-R than S1P5-R. CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM .
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1
1 Cited Publications
製品番号: HY-P701153
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: EBP50; NHERF; NHERF-1; NHERF1; NPHLOP2
Species:  
Source:  
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製品番号: HY-P10849
CAS 番号: 3061802-23-8
Target:  

Calcium Channel

研究分野:  

Others

IP3RPEP6 is an IP3R competitive inhibitor. IP3RPEP6 has the IC50 values of 9.0 μM, 3.9 μM and 4.3 μM for IP3R1, IP3R2 and IP3R3, respectively. IP3RPEP6 does not affect the Ryanodine receptor and Cx43 hemichannels. IP3RPEP6 regulates calcium signaling within cells .
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製品番号: HY-108494
CAS 番号: 1355026-60-6
純度:  99.70%
Target:  

LPL Receptor

研究分野:  

Cardiovascular Disease

CYM50260 is a potent and exquisitely selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonist with an EC50 of 45 nM. CYM50260 displays no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R .
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製品番号: HY-40041
CAS 番号: 163765-44-4
(R)-1-Boc-3-methyl-piperazine (Compound I3-1) is a chemical intermediate. (R)-1-Boc-3-methyl-piperazine can be used for the preparation of Compound I3. Compound I3 exhibits anticancer activity against colorectal adenocarcinoma with BRCA2 gene deletion .
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製品番号: HY-W111383
CAS 番号: 193693-65-1
別名: (R)-1-Fmoc-3-pyrrolidinecarboxylic acid
Target:  

Drug Intermediate

研究分野:  

Others

Fmoc-D-β-Pro-OH ((R)-1-Fmoc-3-pyrrolidinecarboxylic acid) is a drug intermediate for synthesis of various active compounds.
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製品番号: HY-40097
CAS 番号: 147081-49-0
(R)-1-Boc-3-aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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製品番号: HY-P11540
CAS 番号: 2923120-30-1
CCKBR agonist-1 (Compound 3r1) is a Gq-protein-preferring cholecystokinin B receptor (CCKBR) agonist with an EC50 of 35 pM. CCKBR agonist-1 significantly increases the survival rate of neurons, with an EC50 of 37 pM. CCKBR agonist-1 can improve the cognitive decline in mice by upregulating α-secretase (ADAM10) and calcium signaling molecule PLCB4, reduce the number of amyloid β () plaques, and promote long-term potentiation (LTP). CCKBR agonist-1 can be used for the study of Alzheimer's disease .
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製品番号: HY-162774A
Target:  

Apoptosis

研究分野:  

Cancer

GRP75-IN-1 hydrochloride (compound 33) is an anti-endometrial cancer (EC) agent that induces apoptosis. GRP75-IN-1 hydrochloride reduces Ca 2+ levels in mitochondria by targeting GRP75 and disrupting its interaction with IP3R .
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製品番号: HY-111501
CAS 番号: 1429375-54-1
純度:  99.82%
H4R antagonist 1 is a potent and highly selective histamine H4 receptor (H4R) antagonist with an IC50 of 27 nM. H4R antagonist 1 does not show any noticeable binding affinity to other subtypes of histamine receptors, H1R, H2R, and H3R .
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製品番号: HY-P3862
CAS 番号: 110880-53-0
[MePhe7]-Neurokinin B is an neurokinin NK-3 receptor (NK3R) agonist with an IC50 value of 3 nM. [MePhe7]-Neurokinin B is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activation of the neurokinin-3 receptor (NK3R) .
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製品番号: HY-103178
CAS 番号: 252979-43-4
純度:  98.34%
Target:  

Adenosine Receptor

研究分野:  

Inflammation/Immunology

MRE3008F20 is a highly efficient, highly selective and radioactive adenosine A3 receptor (AA3R) antagonist (Ki=1.8 nM). MRE3008F20 effectively antagonises Cl-IB-MECA-induced cAMP production in resting lymphocytes with an IC50 value of 5 nM. MRE3008F20 can be used in the study of AA3R .
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製品番号: HY-161366
CAS 番号: 3033806-03-7
Target:  

PI3K

研究分野:  

Cancer

OMS14 is exhibits inhibitory activity for phosphoinositide 3-kinase γ (PI3Kγ) and PIK3CD/PIK3R1, which inhibits 19% PI3Kγ and 65% PIK3CD/PIK3R1 activity at 100 μM. OMS14 exhibits anticancer efficacy in various cancer cells .
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製品番号: HY-W590670
CAS 番号: 121459-06-1
別名: N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl]icosanamide
C20-Dihydroceramide is a biochemical assay reagent.
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製品番号: HY-100617A
CAS 番号: 7292-81-1
別名: (RS)-4-Carboxyphenylglycine
Target:  

mGluR

研究分野:  

Others

(RS)-4CPG ((RS)-4-Carboxyphenylglycine) is a type I metabotropic glutamate receptor antagonist with activity in blocking LTP induction. In mice lacking IP3R1, (RS)-4CPG (500μM) nearly blocked long-term potentiation (LTP) induced by type I metabotropic glutamate receptor activation, with LTP of 117.6±1.7% (n = 8) in IP3R1(-/-) mice and 116.9±1.8% (n = 5) in IP3R1(+/+) mice.
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製品番号: HY-40062
CAS 番号: 928025-57-4
Target:  

Drug Intermediate

研究分野:  

Others

(R)-1-Boc-3-propylpiperazine is a drug intermediate for synthesis of various active compounds.
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