11 Results for "

951-78-0

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "951-78-0" in MCE Product Catalog:

3
2'-Deoxyuridine
2'-Deoxyuridine
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3 Cited Publications
Cat. No.: HY-D0186
CAS No.: 951-78-0
Category:  

Infection Natural Products Microorganisms Immune System Disorder Disease markers Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Thymidylate Synthase

2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) .
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2'-Deoxyuridine (Standard)
2'-Deoxyuridine (Standard)
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Cat. No.: HY-D0186R
CAS No.: 951-78-0
Category:  

Natural Products Microorganisms Immune System Disorder Disease markers Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite Thymidylate Synthase

2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine. This product is intended for research and analytical applications. 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) . In Vitro:The interaction between the 2-deoxyuridine and the column increases the duration of retention of 2-deoxyuridine .
Gradient elution with sodium acetate buffer-ACN eluent on two ZIC-HILIC homemade columns separates 2-deoxyuridine in under 9 min .
In Vivo:2'-Deoxyuridine (34.42 ng/mL, gavage, 15 min) passes the blood-brain barrier (BBB) to enter the hippocampus of mice brain .
2'-Deoxyuridine (20 mg/kg, gavage, daily for 4 weeks) improves cognition and memory loss and attenuates the damage to the hippocampus in Aβ25-35-induced mice model .
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2'-Deoxyuridine-13C,15N2
2'-Deoxyuridine-13C,15N2
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Cat. No.: HY-D0186S7
CAS No.: 369656-76-8
2'-Deoxyuridine- 13C, 15N2 is the 13C and 15N labeled 2'-Deoxyuridine . 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine .
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2-Deoxyuridine-1,2,3,4,5-13C5
2-Deoxyuridine-1,2,3,4,5-13C5
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Cat. No.: HY-W778990
CAS No.: 478510-94-0
2-Deoxyuridine-1,2,3,4,5- 13C5 is the 13C-labeled 2'-Deoxyuridine (HY-D0186). 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) .
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2'-Deoxyuridine-d2
2'-Deoxyuridine-d2
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Cat. No.: HY-D0186S4
CAS No.: 478511-30-7
2'-Deoxyuridine-d2 is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud
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2'-Deoxyuridine-1′-13C
2'-Deoxyuridine-1′-13C
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Cat. No.: HY-D0186S
CAS No.: 478510-85-9
2'-Deoxyuridine-1′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
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2'-Deoxyuridine-2′-13C
2'-Deoxyuridine-2′-13C
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Cat. No.: HY-D0186S1
CAS No.: 478510-87-1
2'-Deoxyuridine-2′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
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2'-Deoxyuridine-3′-13C
2'-Deoxyuridine-3′-13C
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Cat. No.: HY-D0186S2
CAS No.: 478510-89-3
2'-Deoxyuridine-3′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
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2'-Deoxyuridine-5′-13C
2'-Deoxyuridine-5′-13C
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Cat. No.: HY-D0186S3
CAS No.: 478510-91-7
2'-Deoxyuridine-5′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
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2'-Deoxyuridine-d
2'-Deoxyuridine-d
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Cat. No.: HY-D0186S5
2'-Deoxyuridine-d is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud <
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2'-Deoxyuridine-d2-1
2'-Deoxyuridine-d2-1
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Cat. No.: HY-D0186S8
CAS No.: 40632-23-3
2'-Deoxyuridine-d2-1 is the deuterium labeled 2'-Deoxyuridine . 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine .
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