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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
AND1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "AND1" in MCE Product Catalog:
Target:
Research Areas:
And1-IN-1 is a potent And1 inhibitor with an IC50 of 2.08 μM. And1-IN-1 binds to the N-terminus of And-1 and induces a conformational change in And-1, which promotes the interaction of And-1 with E3 ligase CUL4B for ubiquitin-mediated degradation. And1-IN-1 suppresses the growth of a broad range of cancers and resensitizes platinum-resistant ovarian cancer cells to platinum agents. And1-IN-1 can be used for the studies of ovarian cancer and breast cancer [1].
Cat. No.: HY-162896
CAS No.: 3029132-46-2
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And1 degrader 1 (Compound A15) is a degrader of the acidic nucleoplasmic DNA-binding protein 1 (And1), which can significantly induce the degradation of And1 in NSCLC cells. And1 degrader 1 (5 μM) combined with Olaparib (HY-10162) (1 μM) effectively inhibits the proliferation of A549 and H460 cells. And1 degrader 1 can be used in cancer research [1].
Cat. No.: HY-RS15758
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WDHD1 Human Pre-designed siRNA Set A contains three designed siRNAs for WDHD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22919
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Research Areas:
Wdhd1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Wdhd1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701614
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDHD1; WD repeat AND HMG-box DNA-binding protein 1; Acidic nucleoplasmic DNA-binding protein 1; AND-1
Cat. No.: HY-P701615
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDHD1; WD repeat AND HMG-box DNA-binding protein 1; Acidic nucleoplasmic DNA-binding protein 1; AND-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
