And1 degrader 1
And1 degrader 1 (Compound A15) is a degrader of the acidic nucleoplasmic DNA-binding protein 1 (And1), which can significantly induce the degradation of And1 in NSCLC cells. And1 degrader 1 (5 μM) combined with Olaparib (HY-10162) (1 μM) effectively inhibits the proliferation of A549 and H460 cells. And1 degrader 1 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3029132-46-2
- Formula: C26H27Cl2N3O
- Molecular Weight:468.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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CAS No. 3029132-46-2
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Molecular Weight 468.42
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Formula C26H27Cl2N3O
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SMILES
OC1=CC=C(/C=C/C2=CC=C(Cl)C(Cl)=C2)C=C1CNC3=CC=C(N4CCN(C)CC4)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)