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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Abemaciclib metabolite
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Abemaciclib metabolite" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: LSN3106726
Abemaciclib metabolite M20 (LSN3106726), the active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor for the treatment of cancer .
3
3 Cited Publications
Synonyms: LSN3106729 hydrochloride
Research Areas:
Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader .
3
Target:
Research Areas:
Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s of 1.2 and 1.3 nM, respectively. Anti-cancer activity .
3
Research Areas:
Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader .
Cat. No.: HY-129336S
Purity: 97.01%
Synonyms: LSN3106726-d8
Cat. No.: HY-128669S
Purity: 99.25%
Synonyms: LSN2839567-d6
Cat. No.: HY-126534S
Purity: 98.47%
Synonyms: LSN3106729-d8
Cat. No.: HY-128669R
CAS No.: 1231930-57-6
Synonyms: LSN2839567 (Standard)
Target:
Research Areas:
Abemaciclib metabolite M2 (Standard) is the analytical standard of Abemaciclib metabolite M2. This product is intended for research and analytical applications. Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s of 1.2 and 1.3 nM, respectively. Anti-cancer activity[1][2].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
