1. Cell Cycle/DNA Damage
  2. CDK
  3. Abemaciclib Metabolites M2

Abemaciclib Metabolites M2 

Cat. No.: HY-128669
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Abemaciclib Metabolites M2 is a metabolite of abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s in the range of 1-3 nM. Anti-cancer activity.

For research use only. We do not sell to patients.

Abemaciclib Metabolites M2 Chemical Structure

Abemaciclib Metabolites M2 Chemical Structure

CAS No. : 1231930-57-6

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Description

Abemaciclib Metabolites M2 is a metabolite of abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s in the range of 1-3 nM. Anti-cancer activity[1].

IC50 & Target[1]

CDK4

1-3 nM (IC50)

CDK6

1-3 nM (IC50)

Molecular Weight

478.54

Formula

C₂₅H₂₈F₂N₈

CAS No.

1231930-57-6

SMILES

CC(N1C2=CC(C3=NC(NC4=NC=C(CN5CCNCC5)C=C4)=NC=C3F)=CC(F)=C2N=C1C)C

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Abemaciclib Metabolites M2
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