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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
130 Results for "
Activin A
" in MedChemExpress (MCE) Product Catalog:
Products (130)
130 Results for "Activin A" in MCE Product Catalog:
23
23 Publications Verification
Cat. No.: HY-P70311
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-18 receptor 1; IL-18R1; CDw218a; IL1RRP; IL-18R-alpha; CD218a
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Source:
22
22 Cited Publications
Synonyms: E-616452; SJN 2511
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RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes .
17
17 Cited Publications
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GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, and also inhibits TGF-β type II receptor and activin type II receptor activities, without inhibiting BMP type II receptor.
13
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Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect .
13
13 Cited Publications
Cat. No.: HY-19928A
CAS No.: 1352610-25-3
Synonyms: EW-7197 Hydrochloride; TEW-7197 Hydrochloride
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Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect .
3
3 Cited Publications
Cat. No.: HY-P99355
CAS No.: 1356922-05-8
Synonyms: Anti-ACVR2B Reference Antibody; BYM338
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2
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2
2 Cited Publications
Cat. No.: HY-78349
CAS No.: 607737-87-1
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A 77-01 is a potent inhibitor of transforming growth factor (TGF)-β type I receptor superfamily activin-like kinase ALK5 with an IC50 of 25 nM .
2
2 Cited Publications
Cat. No.: HY-P700159AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: INHBA; Follicle-Stimulating Hormone-Releasing Protein; Inhibin Subunit Beta A; Erythroid Differentiation Factor; Inhibin Beta A Chain; Inhibin Beta A Subunit; Activin Beta-A Chain; FSH-Releasing Protein; Inhibin, Beta A (Activin A, Activin AB Alpha Polype
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1
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1
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1
1 Cited Publications
Cat. No.: HY-P703994
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: INHBA; Follicle-Stimulating Hormone-Releasing Protein; Inhibin Subunit Beta A; Erythroid Differentiation Factor; Inhibin Beta A Chain; Inhibin Beta A Subunit; Activin Beta-A Chain; FSH-Releasing Protein; Inhibin, Beta A (Activin A, Activin AB Alpha Polype
1
1 Cited Publications
Cat. No.: HY-P73241
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: INHBA; Follicle-Stimulating Hormone-Releasing Protein; Inhibin Subunit Beta A; Erythroid Differentiation Factor; Inhibin Beta A Chain; Inhibin Beta A Subunit; Activin Beta-A Chain; FSH-Releasing Protein; Inhibin, Beta A (Activin A, Activin AB Alpha Polype
Cat. No.: HY-P991504
Research Areas:
Cat. No.: HY-P990733
CAS No.: 2769700-97-0
Synonyms: KER-012
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Synonyms: ALK2-IN-4
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KER047 (ALK2-IN-4) is a potent activin receptor-like kinase-2 (ALK2) inhibitor. KER047 can be used for the research of metabolic disease, such as fibrodysplasia ossificans progressiva (FOP).
Cat. No.: HY-P99818
CAS No.: 1169766-01-1
Synonyms: ACE-031
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TP-008, a chemical probe, is a potent, selective and orally active (Activin-Like Kinase 5) ALK5 inhibitor with pIC50 and pEC50 values of 7.6 and 6.63, respectively. TGFβRI-IN-2 can produce observed cardiac toxicity in vivo at high dose .
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M4K2163 dihydrochloride is a potent, selective, blood-brain barrier (BBB) permeable activin receptor-like kinase-2 (ALK2) inhibitor, with an IC50 of 19 nM. M4K2163 dihydrochloride can be used in the research of diffuse intrinsic pontine glioma (DIPG) .
Cat. No.: HY-P990022
CAS No.: 2566473-71-8
Synonyms: DS-6016A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
