452342-67-5
452342-67-5
Chemical Structure
GW788388
- CAS No.: 452342-67-5
- Formula:C25H23N5O2
- Molecular Weight:425.48
IUPAC Name: 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide
InChIKey: SAGZIBJAQGBRQA-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C=C1)C2=NC=CC(C3=CNN=C3C4=NC=CC=C4)=C2)NC5CCOCC5
Biological Activity: GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, and also inhibits TGF-β type II receptor and activin type II receptor activities, without inhibiting BMP type II receptor.
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GW788388 | 99.92% | GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, and also inhibits TGF-β type II receptor and activin type II receptor activities, without inhibiting BMP type II receptor. | ||||||||||||||||||||
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GW788388 (Standard) | ≥98% | GW788388 (Standard) is the analytical standard of GW788388 (HY-10326). This product is intended for research and analytical applications. GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, and also inhibits TGF-β type II receptor and activin type II receptor activities, without inhibiting BMP type II receptor. | ||||||||||||||||||||
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Keywords
